Zalicus, Inc.
Zalicus, Inc. was a U.S. pharmaceutical company (formerly CombinatoRX) focused on developing new drugs from combinations of existing medicines; it was dissolved in 2014.
Last updated September 29, 2026
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Overview
Zalicus, Inc. was an American pharmaceutical company that specialized in investigating the effects of combining different medications in order to create entirely new drugs. The company was originally founded as CombinatoRX by Alexis Borisy and was based at Boston University. In December 2009, CombinatoRX merged with Neuromed Pharmaceuticals, and in September 2010 the combined entity was renamed Zalicus, Inc. The company operated in the United States and pursued a drug-discovery strategy centered on combination therapies. Its corporate life was relatively short: in July 2014, Zalicus was dissolved through a merger with Epirus and was renamed Epirus Biopharmaceuticals. As a result, Zalicus no longer exists as an operating brand or company; its name survives only in historical records and in the domain zalicus.com, which is now listed for sale as a premium brandable domain on the BrandBucket marketplace. The domain listing describes "Zalicus" as a savvy, agile, unique and memorable name suitable for a software developer, a fintech startup, an innovative healthcare technology firm, or a logistics company, but this is a domain-marketplace description and not evidence of an active Zalicus business.
History
Zalicus, Inc. was a U.S. pharmaceutical company that specialized in investigating the effects of combining different medications in order to create entirely new drugs. The business was founded by Alexis Borisy under the name CombinatoRX and was based at Boston University. In December 2009, CombinatoRX merged with Neuromed Pharmaceuticals. In September 2010, the company changed its name to Zalicus, Inc. The company's dissolution occurred in July 2014 through a merger with Epirus and a renaming to Epirus Biopharmaceuticals. After that transaction, Zalicus ceased to exist as an operating company. The zalicus.com domain later appeared for sale as a premium brandable domain name on the BrandBucket marketplace, which markets the name as suitable for a software developer, a fintech startup, an innovative healthcare technology firm, or a logistics company.
CombinatoRX, founded by Alexis Borisy and based at Boston University, operates as a pharmaceutical company.
December 2009: CombinatoRX merges with Neuromed Pharmaceuticals.
September 2010: The company is renamed Zalicus, Inc.
July 2014: Zalicus is dissolved through a merger with Epirus and renamed Epirus Biopharmaceuticals.
Products and positioning
A pharmaceutical research company focused on discovering new drugs by combining existing medications.
Product categories. Combination drug candidates · Pharmaceutical research and development
Sources6 sources
- 1Zalicus.com is For Sale | BrandBucketbrandbucket.com
- 2Zalicus - Wikipedia (German)de.wikipedia.org
- 3Zalicus - Wikidatawikidata.org
- 4The BrandBucket Story: Revolutionizing Business Namingbrandbucket.com
- 5Browse Brandable Business Names | BrandBucketbrandbucket.com
- 6Browse Brandable Business Names | BrandBucketbrandbucket.com
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