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Xtant Medical

A Montana-based tissue bank and orthobiologics company that develops regenerative biologic grafts and complementary spinal implant systems.

Last updated September 26, 2026

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Overview

Xtant Medical is a United States-based medical technology company that operates as a tissue bank and a developer of orthobiologics and spinal fixation systems. Headquartered in Montana, the company describes itself as combining the rigor of science with the heart of purpose, and it traces its origins to a spin-off from Montana State University's Center for Biofilm Engineering. Over time it evolved into Xtant Medical, building a comprehensive portfolio of biologic grafts and spinal implant systems while maintaining its roots in honoring donors and serving patients. At the core of the business are regenerative biologics. Xtant Medical's vertically integrated tissue operations span donor recovery, patented processing, and distribution, which the company says allows it to deliver grafts without compromising safety, quality, and clinical performance. Its biologics are processed in a dedicated, state-of-the-art facility using patented technologies such as BacteRinse, which is designed to preserve essential growth factors while ensuring safety and clinical reliability. The company markets a broad range of orthobiologic solutions, including OsteoFactor Pro, an allogeneic growth factor product that provides a biphasic release to support angiogenesis, chemotaxis, and osteogenesis, as well as the Trivium line of advanced biologic graft options. Complementing its biologics is a portfolio of spinal implants. Xtant Medical offers cervical, thoraco-lumbar, and interbody spinal implant systems used in complex, deformity, and degenerative procedures. These systems are engineered to pair naturally with Xtant biologics, giving surgeons a single, reliable source for both biologic and fixation needs. The company positions this integrated offering as a way to avoid compromising choice or performance, and it emphasizes proven clinical outcomes supported by decades of peer-reviewed data and fusion rates as high as 97.5%. Xtant Medical serves surgeons and patients primarily in the United States, and it also maintains an OEM business and a secure product portal for authorized distributors and partners. The portal provides access to product specifications, technique guides, marketing and sales assets, and order and support tools. The company's stated mission is to honor the gift of donation by allowing patients to live as full and complete a life as possible, and its quality policy commits to designing, manufacturing, and distributing safe and effective medical devices and human tissues for transplant. Xtant Medical is publicly traded in the United States under the ticker XTNT.

History

Xtant Medical's history is rooted in Montana and in the science of biofilm engineering. According to the company, it began as a spin-off from Montana State University's Center for Biofilm Engineering. That academic origin gave the enterprise a research-driven foundation, and over time the organization evolved into Xtant Medical, a company that today describes itself as a tissue bank and a developer of orthobiologics and spinal fixation systems. From its early roots as a Montana-based tissue bank, Xtant Medical grew into what it calls a recognized leader in advanced orthobiologics. The company built a comprehensive biologics portfolio supported by spinal implant systems designed to work seamlessly with its grafts. Its integrated capabilities in tissue processing and biologic innovation allow it to provide surgeons with scientifically engineered solutions for a wide range of procedures. The company states that it has 25 years of clinical success in biologics, and it emphasizes that its vertically integrated operations—from donor recovery to distribution—ensure quality, traceability, and consistency. A central element of the company's development has been its investment in processing technology. Xtant Medical processes its biologics in a dedicated, state-of-the-art facility using patented technologies such as BacteRinse, which is intended to preserve essential growth factors while ensuring safety and clinical reliability. This focus on proprietary processing supports the company's mission to honor every donor gift with high standards of quality and respect. The company also highlights proven clinical outcomes supported by decades of peer-reviewed data and fusion rates as high as 97.5%. Over time, Xtant Medical expanded beyond biologics into spinal implants. It now offers a complementary portfolio of cervical, thoraco-lumbar, and interbody spinal implant systems used in complex, deformity, and degenerative procedures. These systems are engineered to pair naturally with Xtant biologics, giving surgeons a single, reliable source for biologic and fixation needs. The company also operates an OEM business and maintains a secure product portal for authorized distributors and partners, providing product specifications, technique guides, marketing and sales assets, and order and support tools. Today, Xtant Medical is headquartered in Montana and is publicly traded in the United States under the ticker XTNT. Its stated mission is to honor the gift of donation by allowing patients to live as full and complete a life as possible, and its quality policy commits the company to designing, manufacturing, and distributing safe and effective medical devices and human tissues for transplant. The company continues to position itself at the intersection of tissue donation, biologic innovation, and spinal fixation.

  • Originated as a spin-off from Montana State University's Center for Biofilm Engineering.

  • Evolved into Xtant Medical, a tissue bank and developer of orthobiologics and spinal fixation systems.

  • Built a comprehensive biologics portfolio supported by spinal implant systems designed to work with its grafts.

  • Reached 25 years of clinical success in biologics, according to the company.

  • Developed patented processing technologies such as BacteRinse for its biologics.

  • Expanded into a complementary portfolio of cervical, thoraco-lumbar, and interbody spinal implant systems.

Products and positioning

A vertically integrated orthobiologics and spinal fixation company that pairs patented biologic grafts with complementary spinal implant systems, emphasizing safety, traceability, and clinical performance.

  • OsteoFactor Pro

    An allogeneic growth factor product described as a naturally occurring blend of growth factors stabilized in native human collagen, delivering a biphasic release with an immediate burst and sustained delivery to support angiogenesis, chemotaxis, and osteogenesis.

  • Trivium

    A line of advanced biologic graft options offered by Xtant Medical.

  • BacteRinse

    A patented processing technology used to preserve essential growth factors while ensuring safety and clinical reliability in Xtant Medical's biologics.

  • Cervical spinal implant systems

    Spinal implant systems for cervical procedures, engineered to pair with Xtant biologics.

  • Thoraco-lumbar spinal implant systems

    Spinal implant systems for thoraco-lumbar procedures, used in complex, deformity, and degenerative cases.

  • Interbody spinal implant systems

    Interbody spinal implant systems that complement Xtant's biologics portfolio.

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