Wyatt Technology Corporation
Wyatt Technology is a Waters business that supplies light-scattering instruments, software, and analytical services for characterizing proteins, polymers, nanoparticles, and other macromolecules.
Last updated September 25, 2026
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Overview
Wyatt Technology Corporation is a scientific-instrumentation and analytical-solutions business presented on its official website as part of Waters. Its focus is light-scattering instrumentation and software for characterizing macromolecules and nanoparticles in solution. The company describes its tools as enabling measurement of absolute molar mass, size, charge, and molecular interactions. Its applications span biotherapeutics, proteins, polymers, nanoparticles, vaccines, and gene-therapy-related work. For adeno-associated virus (AAV) therapies, Wyatt offers workflows that combine size-exclusion chromatography with multi-angle light scattering (SEC-MALS), high-throughput dynamic light scattering (HT-DLS), and field-flow fractionation with MALS (FFF-MALS). Its stated use cases include measuring capsid concentration, aggregate content, and other critical quality attributes during product development, process development, formulation, quality control, and lot release. The portfolio includes instruments and software as well as related implementation, training, compliance, and service offerings. The official site highlights the ultraDAWN Pilot RT-MALS system for inline or online process analytics, including monitoring biophysical attributes in downstream bioprocessing. Services include AAV method implementation and training, on-site installation and training, service plans, IQ/OQ validation, consulting, and sample analysis. Wyatt also helps prospective users locate academic, government, or commercial contract laboratories equipped with its instruments. The website identifies Santa Barbara, California, as the location for its Light Scattering University training and describes on-site services at customer laboratories. Its contract-laboratory directory includes facilities in North America and Europe. Wyatt is presented under the Waters | Wyatt Technology name, indicating its position within the Waters business; the supplied materials do not establish a founding date, founder, or named current executives.
History
Wyatt Technology is represented on its current official website as part of Waters. The available evidence describes the business through its instrumentation, analytical methods, and customer services rather than providing a corporate founding chronology. No founding date, founder, or dated early-history events are established by the supplied sources. The company’s documented focus is light-scattering instrumentation and software used to characterize proteins, polymers, nanoparticles, and other macromolecules in solution. The website describes measurements including absolute molar mass, size, charge, and interactions. Its applications include biotherapeutics and gene-therapy workflows, where analytical characterization can support development and process decisions. A prominent current offering is ultraDAWN Pilot RT-MALS, described as extending inline and online real-time multi-angle light-scattering process analytics to pilot scale. The official site lists applications such as monitoring biologics, viral vectors, nanoparticles, and conjugates during downstream unit operations. For AAV-based therapies, Wyatt describes SEC-MALS, HT-DLS, and FFF-MALS methods for measuring critical quality attributes, alongside implementation and training services and SOP guidance. Wyatt’s customer support extends beyond instrument sales. Its official materials describe on-site installation and training, service plans, instrument compliance documentation and IQ/OQ validation, consulting, and sample analysis. It also maintains a directory of third-party academic, government, and commercial laboratories that offer contract analytical services using Wyatt instruments. The supplied materials do not provide dated ownership milestones, leadership changes, or other historical events.
Products and positioning
A specialist provider of light-scattering instrumentation, software, and services for biopharmaceutical, biotechnology, and materials characterization workflows.
ultraDAWN Pilot RT-MALS
A real-time multi-angle light-scattering detector for inline or online process analytics, described for pilot-scale monitoring of biophysical attributes during downstream operations.
SEC-MALS AAV characterization
A method offering automated measurement of AAV-related critical quality attributes, including capsid concentration and aggregate content.
HT-DLS and FFF-MALS
High-throughput dynamic light scattering and field-flow fractionation with multi-angle light scattering, presented as techniques for AAV characterization.
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