ViridisChem
ViridisChem is a San Jose-based cheminformatics company whose AI-powered platform helps R&D and EHS teams design safer, more sustainable chemicals and generate regulatory-compliant safety data sheets.
Last updated September 29, 2026
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Overview
ViridisChem is an American cheminformatics and green-chemistry software company headquartered in San Jose, California. It builds an AI-powered chemistry platform aimed at R&D and Environment, Health and Safety (EHS) teams, helping them prioritize sustainability, scalability and performance during product development. The company positions itself around the idea that toxicity data should be available early in the design process, so that scientists can avoid late-stage reformulation and choose functionally equivalent but less hazardous chemicals. The core of the offering is a cheminformatics platform that combines a large toxicity database, a properties predictor, scoring calculators and generative-AI features. According to the company, its toxicity database contains profiles of over 100 million compounds, with 28 properties per chemical covering physical, functional and toxicological characteristics, EHS implications and industrial uses. A "Properties Predictor" uses more than 150 AI-driven prediction models to estimate on-demand profiles of proprietary chemicals, novel molecules, their metabolites and analogs. These capabilities feed into products such as the Chemical Analyzer, Reaction Analyzer and SDS Builder. The SDS Builder is a notable commercial product: it generates Safety Data Sheets for chemicals, proprietary compounds and complex mixtures, and the company states that these are compliant with US-OSHA, REACH/GHS and WHMIS guidelines, available in multiple languages, and include OEL limits from over 15 countries and regulatory information from over 150 lists. ViridisChem markets the SDS Builder as exceeding upcoming regulatory mandates, including August 2026 US-OSHA requirements, and as supporting mixtures with up to 50 ingredients while allowing manufacturers to hide ingredient identities. Beyond SDS generation, the platform supports novel molecule research (predictive properties and ADMET profiles for drug candidates and metabolites), product development (route feasibility, scalability, EHS impact and waste scoring), and safer, sustainable chemistry (identifying toxic reagents and mixtures and finding safer alternatives). The company offers free trials of the SDS Builder, Chemical Analyzer and Reaction Analyzer. ViridisChem has received recognition for its sustainability focus. In 2017 the United Nations Environment Programme (UNEP) recognized it as one of the most innovative startups influencing sustainability, and it won the LAUNCH.ORG "Innovations for Chemistry" award. It was also accepted into the Plug and Play startup accelerator program in 2017, and in 2018 the Silicon Valley Business Journal recognized it as a noteworthy startup pushing for greener, sustainable work in chemistry. The leadership team includes co-founder and CEO Neelam Vaidya and CTO Rahul Vaidya, supported by a roster of business and technical advisors.
History
ViridisChem is a privately held cheminformatics company based in San Jose, California, in the United States. It was co-founded by Neelam Vaidya, who serves as CEO and has led the company's efforts to bring toxicity-focused software solutions to product development across industries. The company's mission centers on the potential of green chemistry to create a better world, and it seeks to empower scientists in many industries to build a more sustainable future through critical toxicity analysis for smarter decision-making. The company emerged as part of a wave of startups applying artificial intelligence and big data to chemistry and sustainability challenges. Its platform was built around a large curated toxicity database, which the company says contains profiles of over 100 million compounds, with data collected from reputed sources around the world, updated constantly, and curated over roughly a decade using internal AI-driven tools. Each chemical profile includes 28 properties spanning physical, functional and toxicological characteristics, EHS implications and industrial uses. In 2017 ViridisChem received significant external recognition. The United Nations Environment Programme (UNEP) recognized it as one of the most innovative startups to influence sustainability. In the same year it won the global LAUNCH.ORG "Innovations for Chemistry" award and was accepted into the Plug and Play startup accelerator program. In 2018 the Silicon Valley Business Journal recognized ViridisChem as a noteworthy startup pushing for greener, sustainable work in chemistry. Over time the company expanded its platform from a toxicity database and properties predictor into a suite of applied products. The Properties Predictor uses over 150 AI-driven prediction models to offer on-demand, real-time predicted profiles of proprietary chemicals, novel molecules, their metabolites and analogs, enabling qualitative screening of drug candidates within days. The Scores Calculator uses individual chemical physical and toxicological properties, regulatory information and proprietary algorithms to provide chemical- and reaction-related scores. Commercial products built on the platform include the Chemical Analyzer, which provides comprehensive chemical profiles and helps users select functionally equivalent least-toxic chemicals; the Reaction Analyzer, which provides predictive scores of reactions for performance, toxicity, waste and scalability and identifies toxic reagents and by-products; and the SDS Builder, which generates Safety Data Sheets for known chemicals, proprietary compounds and complex mixtures. The SDS Builder combines the Toxicity Database and Properties Predictor to produce data-rich SDS in multiple languages, compliant with US-OSHA, REACH/GHS and WHMIS guidelines, including OEL limits from over 15 countries and regulatory information from over 150 lists. The company markets it as exceeding the August 2026 US-OSHA regulatory mandates and as supporting complex mixtures and formulations with up to 50 ingredients, while allowing manufacturers to hide ingredient identities. The company also introduced generative-AI capabilities into its platform, marketed as ViridisChem Gen-AI, to support toxicity-aware decision-making. Its solutions are organized around four areas: Novel Molecule Research, Product Development, Safer-Sustainable Chemicals, and EHS-Regulatory Compliance. ViridisChem offers free trials of its SDS Builder, Chemical Analyzer and Reaction Analyzer to attract users. Leadership includes CEO Neelam Vaidya and CTO Rahul Vaidya, supported by a team of business, technical and marketing advisors including Anton Gueth, Steve Lamont, Dr. David Constable, Lucy Reckseit, Dr. Niteen A. Vaidya, Khanderao Kand, Dr. Ving Lee, Hans Plugge, Pam Spencer and Laurie Kretchmar. The company remains privately held and continues to operate from San Jose, California.
- 2018
Silicon Valley Business Journal recognizes ViridisChem as a noteworthy startup pushing for greener, sustainable work in chemistry.
- 2017
UNEP recognizes ViridisChem as one of the most innovative startups to influence sustainability.
- 2017
ViridisChem wins the global LAUNCH.ORG 'Innovations for Chemistry' award.
- 2017
ViridisChem is accepted into the Plug and Play startup accelerator program.
Products and positioning
AI-powered cheminformatics platform for sustainable, toxicity-aware chemistry in R&D and EHS workflows.
ViridisChem Platform
A cheminformatics platform including comprehensive databases, a properties predictor, unique products and generative AI to help scientists adopt sustainability and define robust, commercially viable product development processes with minimum toxicity footprint.
Toxicity Database
One of the largest toxicity databases, containing profiles of over 100 million compounds with 28 properties per chemical (physical, functional and toxicological), EHS implications and industrial uses, curated over the past 10 years using internal AI-driven tools.
Properties Predictor
A module using over 150 AI-driven prediction models to offer on-demand, real-time predicted profiles of proprietary chemicals, novel molecules, their metabolites and analogs.
Scores Calculator
A module that uses individual chemical physical and toxicological properties, regulatory information and proprietary algorithms to provide chemical- and reaction-related scores.
Chemical Analyzer
Provides comprehensive chemical profiles and helps users select functionally equivalent least-toxic chemicals using advanced searchability.
Reaction Analyzer
Provides predictive scores of reactions for performance, toxicity, waste and scalability, and identifies toxic reagents and by-products.
SDS Builder
Generates data-rich Safety Data Sheets for chemicals, proprietary compounds and complex mixtures, compliant with US-OSHA, REACH/GHS and WHMIS guidelines, in multiple languages, including OEL limits from over 15 countries and regulatory information from over 150 lists.
ViridisChem Gen-AI
Generative AI capabilities integrated into the platform to support toxicity-aware smart decisions.
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