USB Corporation
USB Corporation was a life-science products company supplying tools for molecular biology, biochemical research, drug discovery, and molecular diagnostics.
Last updated August 26, 2026
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History
USB Corporation's history reached back to the 1980s, when the business was known as United States Biochemical. It developed products for molecular biology and biochemical research at a time when DNA sequencing, cloning, and nucleic-acid analysis were becoming increasingly important laboratory activities. The company's work was directed primarily toward specialized research and diagnostic users rather than general consumers. One of the products most closely associated with the company was Sequenase DNA Polymerase. This genetically modified enzyme was used in the development of DNA-sequencing products designed to make sequencing procedures easier to use. Its role connected USB with the broader development of practical molecular-biology methods, in which improved enzymes and ready-to-use reagents helped laboratories perform procedures that had previously required more complex preparation or technical expertise. Over time, USB's activities expanded beyond sequencing-related products. The company supplied tools and reagents for DNA amplification using polymerase chain reaction, purification of nucleic acids, molecular cloning, protein studies, and RNA analysis. These areas formed a connected portfolio: researchers could use such products to prepare biological material, copy or isolate DNA, construct and analyze molecular clones, investigate proteins, and study RNA. The available reference does not provide a full chronological list of product launches, facilities, executives, or changes in corporate structure during this period. A major corporate change occurred at the beginning of 2008, when Affymetrix acquired USB Corporation. The acquisition ended or substantially changed USB's position as an independent company, although the supplied material does not specify the transaction's financial terms, the exact structure of the integration, or the subsequent treatment of the USB name and product lines. Affymetrix's ownership is therefore the final documented milestone in this dossier. Further information would be required to determine whether USB remained an active standalone brand after the acquisition.
- 2008
Acquisition by Affymetrix
[1]Affymetrix acquired USB Corporation at the beginning of 2008.
- 1980
Business history begins as United States Biochemical
[1]The company's documented history reaches back to the 1980s, when it was known as United States Biochemical and operated in the molecular-biology and biochemical research field.
Development and use of Sequenase DNA Polymerase
[1]USB became associated with Sequenase DNA Polymerase, a genetically modified enzyme used in the development of easier-to-use DNA-sequencing products.
Products and positioning
A specialist life-science supplier focused on molecular-biology and biochemical research workflows, including DNA sequencing, amplification, purification, cloning, protein studies, and RNA analysis.
DNA sequencing enzyme
Sequenase DNA Polymerase
A genetically modified DNA polymerase associated with USB's contribution to easier-to-use DNA-sequencing products. It was a key offering in the company's historical identity and connected USB with the development of practical sequencing workflows for molecular-biology laboratories.
Molecular biology reagents
PCR and DNA amplification products
A group of reagents and laboratory products intended to support polymerase chain reaction and related DNA-amplification procedures. These products formed part of USB's broader molecular-biology portfolio for research and analytical workflows.
Laboratory preparation products
Nucleic-acid purification products
Products used in the purification and preparation of DNA or other nucleic acids before downstream molecular-biology procedures. The available material identifies purification as one of USB's principal areas but does not specify individual product names.
Molecular biology reagents
Molecular cloning products
Reagents and tools supporting molecular cloning workflows, including the manipulation and analysis of cloned genetic material. The supplied reference identifies cloning as a core application area without providing a detailed product catalog.
Biochemical research products
Protein and RNA analysis products
A broad set of biochemical and molecular-biology products for protein studies and RNA analysis. These offerings extended USB's scope beyond DNA sequencing and amplification into other major research workflows.
Brand decisions
2008
Affymetrix acquisitionM&ABackground
USB Corporation operated as a specialist supplier of molecular-biology and biochemical products, including sequencing enzymes and products for DNA, RNA, and protein workflows.
Action taken
Affymetrix acquired USB Corporation at the beginning of 2008.
Aftermath
The available reference does not specify the financial terms, integration arrangements, or whether USB continued as an independent brand after the acquisition.
Sources1 sources
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