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Synthego

Synthego is a CRISPR solutions provider offering scalable CRISPR and molecular diagnostics products and services for life science research and therapeutic development.

Last updated September 15, 2026

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Overview

Synthego is a CRISPR solutions provider that enables the acceleration of life science research and development in the pursuit of improved human health. It describes itself as a pioneering force in the biotechnology industry, dedicated to advancing the frontiers of CRISPR cell and gene therapies through CRISPR technology and expertise. Its mission is to provide access to CRISPR solutions at scale, empowering applications from discovery to the clinic, and it states that its technologies have been cited in hundreds of peer-reviewed publications and utilized by thousands of commercial and academic researchers and therapeutic drug developers. Its offerings span CRISPR gene editing research-use-only gRNA, engineered nucleases, CRISPR base editing, GMP manufacturing, GMP gRNA, GMP gene editors, IND submission support, and molecular biology products such as isothermal amplification and PCR & RT enzymes. Synthego Holdings LLC is named as the selling entity in its terms of sale.

History

Synthego is described as a company in Menlo Park, United States. It presents itself as a CRISPR solutions provider that enables the acceleration of life science research and development in the pursuit of improved human health, and as a pioneering force in the biotechnology industry dedicated to advancing the frontiers of CRISPR cell and gene therapies. Its stated mission is to provide access to CRISPR solutions at scale, empowering applications from discovery to the clinic, with the aim of bridging the gap between genomic discoveries and clinical applications. The company states that its technologies have been cited in hundreds of peer-reviewed publications and utilized by thousands of commercial and academic researchers and therapeutic drug developers. Its terms of sale identify Synthego Holdings LLC as the selling entity for its Research Use Only products and for its GMP, INDe, and iPSC RNA products and services.

Products and positioning

A CRISPR solutions provider delivering high-quality, scalable solutions for CRISPR research, molecular biology and diagnostic workflows, with a focus on enabling cell and gene therapy from discovery through clinical trials.

  • Custom Nuclease Manufacturing

    Custom CRISPR gene editors available in mRNA or protein formats for clinical applications.

  • Cell-Free Protein Expression Kit

    Rapid, high-yield protein production in a controlled, scalable system without the need for live cells.

  • AccuBase CBE

    Engineered Cytosine Base Editor eliminates double-strand breaks for safer CRISPR-based therapeutics.

  • hfCas12Max Nuclease

    High-fidelity and flexibility for more efficient cell & gene therapies.

  • RPA Endpoint Kit

    Reliable DNA amplification with endpoint detection and results in minutes.

  • T7 Polymerase

    Engineered RNA polymerase, generating high yields of RNA for mRNA therapeutics.

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