SynBalance SRL
Corporate brand
UnclaimedItalian probiotic biotechnology company spun off from ROELMI HPC in 2022, developing proprietary clinically tested probiotic strains and finished formulations.
Last updated September 29, 2026
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Overview
SynBalance SRL is an Italian biotechnology company focused on the design, development and manufacture of probiotic bacteria. Based in Origgio, Italy, it was established in 2022 as a spin-off of ROELMI HPC, carrying with it roughly 15 years of accumulated experience in the probiotics field. The company positions itself as a business-to-business partner for the nutraceutical, pharmaceutical and personal-care industries, supplying proprietary strains belonging to Lactobacilli, Bifidobacteria and other species produced through bio-fermentation technology. SynBalance's offering spans ingredient development and finished-product formulation. The company emphasizes clinically tested concepts, complete product dossiers and ready-to-go formulations, allowing customers to select the most suitable strain for a given health target and to bring products to market quickly. Its R&D department tracks market trends and pursues cause-effect studies on short- and medium-term projects, supporting a multi-faceted scientific approach built on a network of researchers. The company markets its capabilities through three main probiotic approaches, each backed by a distinct technology. It also offers a portfolio of finished consumer concepts under the YouFirst Collection, including AllerBloom with AllergAway for seasonal allergies, Beautiful Mind with KeepCalm for mood and stress, FlorElle with Femme for women's health, KidBiome with HappyBelly for children's gastrointestinal health, Master&Pro with DefensePlus for immune support, Metabholistic with MetSyn for metabolic health, Senior&Pro with Wellderly for the elderly, Skin Radiance with ProBeautyShield for skin conditions, and YouGut with SmilinGut for gut microbiota restoration. SynBalance highlights a global presence, serving customers from small businesses to multinationals across different countries and industries. It leverages the "Made in Italy" label as a guarantee of quality, safety and reliability, and maintains certifications that allow it to comply with strict regulatory requirements in various jurisdictions. The company describes itself as aiming to become a leader in biotechnology, building on its scientific heritage of in-vitro and clinical trials, patents, scientific publications, awards and registered trademarks.
History
SynBalance SRL was born in 2022 as a spin-off of ROELMI HPC, an Italian company active in the health and personal care ingredients sector. The new entity was created to concentrate and expand probiotics expertise that had been developed within ROELMI HPC over roughly 15 years. According to the company's own account, its probiotics journey began in 2010 with the entry into the probiotics market through Principium B.S.I. – Beauty System & Innovations, an initiative aimed at developing and adapting the benefits of science for beauty and wellness applications. Over the years preceding the spin-off, the team accumulated experience in probiotic strain development, bio-fermentation and finished-product formulation, completing a large number of projects at worldwide level and building a network of researchers. This scientific heritage is presented by the company as the foundation of its multi-faceted approach, supported by in-vitro trials, clinical trials, pending and granted patents, scientific publications, awards and registered trademarks. Following its establishment as an independent company based in Origgio, Italy, SynBalance positioned itself as a business-to-business partner for the nutraceutical and related industries. It developed a portfolio of proprietary strains belonging to Lactobacilli, Bifidobacteria and other species, produced through cutting-edge bio-fermentation technology, and organized its offering around three main probiotic approaches, each with an innovative technology behind it. The company also built a range of finished consumer concepts marketed as the YouFirst Collection, pairing branded probiotic strains with specific health targets such as allergies, mood and stress, women's health, children's gastrointestinal health, immune support, metabolic health, healthy aging, skin conditions and gut microbiota restoration. These concepts are designed to be ready-to-go formulations that customers can adapt to their own markets and pharmaceutical forms. SynBalance emphasizes global reach, serving customers from small companies to multinationals across different countries and industries, and highlights the "Made in Italy" label together with its certifications as evidence of quality, safety and reliability. The company states its ambition to become a leader in biotechnology, continuing to invest in R&D and in cause-effect studies on short- and medium-term projects.
- 2022
SynBalance SRL founded as a spin-off of ROELMI HPC.
- 2010
Entry into the probiotics market with Principium B.S.I. – Beauty System & Innovations.
Products and positioning
B2B probiotic biotechnology partner offering clinically tested, customizable and ready-to-go probiotic solutions with a "Made in Italy" quality guarantee.
AllerBloom with AllergAway
Tailored to aid adults and kids with seasonal allergies and allergic rhinitis.
Beautiful Mind with KeepCalm
For mood, stress and anxiety management in different situations of everyday life, thanks to the bidirectional communication between the gut and the brain.
FlorElle with Femme
For women across all life stages.
KidBiome with HappyBelly
Promotes children's gastrointestinal health, offering effective relief from colics and abdominal pain, restoring gut eubiosis.
Master&Pro with DefensePlus
Designed to boost adults' immune systems during seasonal changes.
Metabholistic with MetSyn
Designed to help control levels of cholesterol, triglycerides and insulin, improving the overall quality of life.
Senior&Pro with Wellderly
For the elderly population, supporting their immune system and improving gut microbiota diversity.
Skin Radiance with ProBeautyShield
Designed to support atopic and acneic skin conditions, rebalancing the gut-skin axis from within.
YouGut with SmilinGut
Designed to restore gut microbiota from dysbiosis, tested on a IBS-like condition improving its symptoms and ensuring GI colonization.
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