SwissLumix

SwissLumix is a Swiss life-science company based at the EPFL Innovation Park in Lausanne that develops and supplies reagents and services for in vitro and in vivo optical imaging. Its product range is built around bioluminescence and fluorescence detection, allowing researchers to visualise and quantify biological processes and molecular pathways in living cells and animals. The company states that its reagents support extremely sensitive imaging and quantification across areas such as oncology, nutrient metabolism and infectious diseases. The core catalogue includes D-Luciferin Potassium Salt (K+), the classic bioluminescent substrate that emits yellow-green light when oxidised by luciferase in the presence of cofactors such as ATP, Mg2+ and oxygen. SwissLumix also offers ready-to-use injectable luciferin kits, luciferase-labelled mammalian cell lines engineered with ultra-bright luc2 luciferase for in vivo work, and caged luciferin reagents designed to monitor biological processes in living systems. Its bioluminescent oncology cell lines cover breast, colorectal, prostate, lung and lymphoma models, and can be dual-labelled with luciferase and fluorescent reporters such as GFP so that tumour growth can be measured immediately after injection, before tumours become palpable. The company also lists specialised probes such as Bioluminescent Glucose Luciferin (BiGLuc) for real-time glucose-uptake imaging and Fatty Acid Luciferin for imaging fatty-acid fluxes. Beyond catalogue products, SwissLumix provides contract development services. These include custom production and validation of luciferase-labelled tumour and bacterial cell lines, custom lentiviral packaging with high-titre virus particles delivered in as little as ten days, development of imaging reagents, and in vivo contract research services. The company positions itself as a specialist partner for academic and industrial laboratories that need sensitive optical imaging tools and ready-to-use biological models. SwissLumix operates from Lausanne and serves research customers internationally, with contact through a Swiss phone number, email and a web contact form. It is a privately held company; no parent group, stock listing or founder information is given in the available sources. Its public identity is that of a focused reagent and service provider rather than a large pharmaceutical or diagnostics corporation.

SwissLumix is a Swiss life-science company located at the EPFL Innovation Park in Lausanne, Switzerland. Public information about the company is limited, and the available sources do not record a founding date, founder names or ownership structure. What is documented is its current activity: the development and supply of reagents and services for in vitro and in vivo optical imaging. The company built its offering around bioluminescence, the light-emitting reaction between luciferase enzymes and luciferin substrates. Its catalogue centres on D-Luciferin Potassium Salt (K+), a widely used substrate that emits yellow-green light upon oxidation by luciferase in the presence of cofactors such as ATP, Mg2+ and oxygen. SwissLumix supplies this substrate in multiple pack sizes and also offers ready-to-use injectable luciferin kits for animal imaging. To support in vivo research, SwissLumix developed luciferase-labelled mammalian cell lines using ultra-bright luc2 luciferase. Its bioluminescent oncology cell lines span breast, colorectal, prostate, lung and lymphoma models, and some lines are dual-labelled with luciferase and fluorescent reporters such as GFP. According to the company, these cells are bright enough to allow tumour growth to be measured immediately after injection, well before tumours become palpable, enabling data collection at time points that traditional calliper measurements cannot reach. The company states that its oncology cell lines are confirmed pathogen free. SwissLumix also expanded into bioactivatable and targeted probes. Bioluminescent Glucose Luciferin (BiGLuc) was developed as a bioluminescent glucose-uptake probe for real-time, non-invasive longitudinal imaging of glucose absorption in vitro and in vivo. Fatty Acid Luciferin is a bioactivatable molecular imaging probe for real-time bioluminescent imaging of fatty-acid fluxes in cell culture and living animals; it conjugates a luciferin molecule to a long-chain fatty acid via a cleavable disulfide bond that is stable extracellularly but reduced intracellularly by glutathione after lipid uptake. The company additionally lists fluorescent targeted imaging agents, dyes and labelling kits. Alongside products, SwissLumix offers contract development services. These include custom production and validation of luciferase-labelled tumour and bacterial cell lines, custom lentiviral packaging that produces high-quality, high-titre virus particles from a customer's lentivector construct in as little as ten days, development of imaging reagents, and in vivo contract research services. The company markets itself under the tagline "Shining Light on Biology" and serves research customers from its Lausanne base, with contact available by phone, email and web form.

Specialist supplier of sensitive bioluminescent and fluorescent optical imaging reagents, labelled cell lines and custom development services for preclinical life-science research.

• D-Luciferin Potassium Salt (K+)

  Bioluminescent substrate used for imaging and quantification of luciferase expression; emits yellow-green light upon oxidation by luciferase in the presence of ATP, Mg2+ and oxygen. Catalog number SL30101, available in 100 mg, 1 g and 5 g pack sizes.

• Luciferase Labelled Cell Lines

  Light-producing oncology and stem cell lines labelled with luciferase or dual-labelled with luciferase and fluorescent reporters (GFP); cover breast, colorectal, prostate, lung and lymphoma models and are confirmed pathogen free.

• Bioluminescent Glucose Luciferin (BiGLuc)

  Bioluminescent glucose-uptake probe for real-time, non-invasive longitudinal imaging of glucose absorption in vitro and in vivo.

• Fatty Acid Luciferin

  Bioactivatable molecular imaging probe for real-time bioluminescent imaging of fatty-acid fluxes in cell culture and living animals; luciferin conjugated to a long-chain fatty acid via a cleavable disulfide bond.

• Custom Lentiviral Packaging

  Production of high-quality, high-titre virus particles using a customer's lentivector construct in as little as 10 days.

• Stable Cell Line Development Services

  Custom production and validation of luciferase-labelled tumour and bacterial cell lines.

1. 1In Vitro and In Vivo Optical Imaging Reagents and Products - SwissLumixswisslumix.com
2. 2In Vitro and In Vivo Optical Imaging Reagents and Productsswisslumix.com
3. 3Contract Development Services - SwissLumixswisslumix.com
4. 4SwissLumix (Switzerland) - Wikidatawikidata.org