Silantes GmbH

Silantes GmbH is a German biotechnology company based in Munich that produces and distributes stable isotope labeled biomolecules for nuclear magnetic resonance (NMR) spectroscopy and quantitative mass spectrometry, including proteomics and metabolomics applications. The company's products are more than 98% isotopically enriched with the isotopes 2H, 13C, 15N, 18O, and 19F. Its core technology, developed in 1998 by Dr. Hermann Heumann at the Max Planck Institute of Biochemistry, is based on the fermentation of chemolithoautotrophic bacteria in closed systems. This purely biotechnological approach converts simple inorganic stable isotope labeled molecules into complex organic molecules such as amino acids, peptides, proteins, nucleotides, RNA, and DNA. Silantes positions itself as a spin-off of a renowned academic institute and emphasizes the quality and cost efficiency of metabolic labeling compared to chemical production methods. The company offers a broad catalog of labeled products, including amino acids, nucleotides, bacterial extracts, and deuterium oxide, and provides customer support, short delivery times, and transparent pricing. Silantes has received recognition for its innovations, including the "Innovative Through Research" seal from the Stifterverband and funding from the German Federal Ministry of Education and Research for a zero-waste production technology. The company also hosts a free webinar series featuring researchers who use its products, and it attends and sponsors scientific conferences.

Silantes GmbH was founded as a spin-off from the Max Planck Institute of Biochemistry in Martinsried, near Munich, Germany. The core technology was developed in 1998 by Dr. Hermann Heumann at the institute. The company was established to commercialize this technology for producing stable isotope labeled biomolecules. The technology is based on the ability of chemolithoautotrophic bacteria to metabolize inorganic carbon, similar to green plants, but with higher productivity and the ability to express heterologous proteins. These bacteria are used as factories to produce stable isotope labeled biomolecules with outstanding homogeneity, especially for triple-labeled (2H, 13C, 15N) biomolecules. Over the years, Silantes has expanded its product portfolio to include a wide range of labeled amino acids, nucleotides, proteins, and other biomolecules for NMR and mass spectrometry. The company has received recognition for its innovations, including the "Innovative Through Research" seal from the Stifterverband and funding from the German Federal Ministry of Education and Research for a zero-waste production technology. Silantes continues to operate as a private company headquartered in Munich, serving research customers worldwide.

• 2024

  Hosted webinars featuring Prof. Dr. Marcus Krüger, Dr. Jürgen Cox, Dr. Chris Turck, and Dr. Junji Iwahara.

• 1998

  Technology developed by Dr. Hermann Heumann at the Max Planck Institute of Biochemistry.

• Silantes GmbH founded as a spin-off from the Max Planck Institute of Biochemistry.

• Received "Innovative Through Research" seal from Stifterverband.

• Awarded funding by the Federal Ministry of Education and Research for zero-waste production technology.

Premium provider of high-quality, biotechnologically produced stable isotope labeled biomolecules for life science research, emphasizing innovation, reliability, and cost efficiency.

• (Fmoc)-L-Arginine(Pbf)-OH

  Stable isotope labeled amino acid derivative for peptide synthesis.

• (Fmoc)-L-Lysine(Boc)-OH

  Stable isotope labeled amino acid derivative for peptide synthesis.

• 1,3-15N,2-13C N1-Methyl-Pseudouridine-5'-O-monophosphate, lithium salt

  Stable isotope labeled nucleotide for RNA research.

• Adenine

  Stable isotope labeled nucleobase.

• Cupriavidus necator (Ralstonia eutropha) Bacterial Extract

  Hydrolysate of protein fractions for labeled proteomics.

• Deuterium oxide > 99.90 atom %

  Heavy water for NMR and other applications.

1. 1Stable Isotope Labeled Biomolecules | Silantessilantes.com
2. 2About Silantes | Innovative Munich Biotech Companysilantes.com
3. 3Webinars | Silantes Stable Isotope Labeled Biomoleculessilantes.com
4. 4All Products Overview | Silantessilantes.com
5. 5Silantes GmbH - Wikidatawikidata.org