Shanghai Model Organisms Center, Inc.

Shanghai Model Organisms Center, Inc. (南模生物, often abbreviated SMOC) is a Chinese life-sciences company focused on the development, breeding, and analysis of genetically modified model organisms. Founded in September 2000 and headquartered in Shanghai, the company describes its mission as "editing genes and decoding life," and it serves universities, research institutes, hospitals, and pharmaceutical companies worldwide with model resources and related technical services. The company's core offering is a large catalog of ready-made genetically modified mouse models — the official website states it holds more than 18,000 finished models, and company materials cite over 20,000 finished mouse models available for selection. These cover drug-target humanized mice, immunology research mice, tool mice (including Cre tool lines), cell-line resources, disease models, and conventional mouse strains. Beyond catalog models, SMOC provides custom genetically modified model generation, pharmacology and efficacy studies, and other preclinical research services such as safety evaluation and pharmacokinetics. SMOC operates multiple facilities in and around Shanghai, including a headquarters on Hupo Road, an R&D center on Banxia Road, CRO services in Zhangjiang, and housing and breeding operations in Jinshan. It also maintains breeding capacity in Zhongshan, Guangdong, and in Sugar Land, Texas, in the United States, supporting both domestic and international clients. The company emphasizes five leading core technology platforms and more than two decades of large barrier-facility operation experience. In December 2021, Shanghai Model Organisms listed on the STAR Market of the Shanghai Stock Exchange under the stock abbreviation 南模生物 and ticker 688265. The company continues to expand its model catalog and service offerings, announcing new disease models and facility openings, such as the Jinke Center base, as part of its growth in the preclinical research tools market.

Shanghai Model Organisms Center, Inc. was established in September 2000 in Shanghai, founded with the aim of "editing genes and decoding life" and focusing on the model organism field. From its early years, the company specialized in the development, breeding, and analysis of genetically modified animal models, building a business around supplying model resources and technical services to universities, research institutes, hospitals, and pharmaceutical companies. Over more than two decades, SMOC expanded its model catalog and service capabilities. It developed core technology platforms for gene editing and model generation, and accumulated extensive experience operating large barrier facilities for laboratory animal housing and breeding. The company grew its finished model library to more than 18,000 models, covering areas such as drug-target humanization, immunology, neuroscience, metabolic and cardiovascular disease, and rare diseases. It also built out tool resources including Cre tool mice, reporter and fluorescent tracer lines, and cell-line resources. Geographically, SMOC established multiple facilities in Shanghai and beyond. Its headquarters is located on Hupo Road in Pudong, with an R&D center on Banxia Road, CRO services in Zhangjiang, and housing and breeding operations in Jinshan. The company also set up breeding capacity in Zhongshan, Guangdong, and in Sugar Land, Texas, in the United States, reflecting its ambition to serve international clients. A Jinshan R&D base was put into operation to support gene-modified rat and mouse R&D, strain preservation, and phenotype analysis. A major milestone came on December 28, 2021, when Shanghai Model Organisms listed on the STAR Market of the Shanghai Stock Exchange under the stock abbreviation 南模生物 and ticker 688265. The listing provided capital to further expand model resources and services. In subsequent years, the company continued to launch new disease models and services — for example, the Myh6-R404Q mouse model and cardiac ultrasound service for hypertrophic cardiomyopathy — and inaugurated new facilities such as the Jinke Center base. As of the mid-2020s, SMOC positions itself as a leading Chinese provider of genetically modified animal models and preclinical research services.

• Shanghai Model Organisms Center, Inc. founded in Shanghai.

• Listed on the STAR Market of the Shanghai Stock Exchange under ticker 688265.

• Jinke Center base officially inaugurated.

• Launched Myh6-R404Q mouse model and cardiac ultrasound service for hypertrophic cardiomyopathy.

Provider of comprehensive, convenient, and professional model organism technical services and model resources for basic research and drug development.

• Drug-target humanized mice

  Models for drug screening, efficacy evaluation, and safety assessment.

• Immunology research mice

  Includes immunodeficient and immune-tracing models for immunology and oncology research.

• Cre tool mice

  A comprehensive set of Cre tool lines for conditional gene manipulation.

• Cell line resources

  Includes fluorescent tracer cells and humanized mouse cells for transplantation tumor efficacy models.

• Custom genetically modified model generation

  Uses the SmartEddi intelligent system to rapidly generate mouse model customization plans.

• Pharmacology and efficacy studies

  Provides suitable animal models to test drug efficacy according to client needs.

• Other preclinical research

  Covers safety evaluation, pharmacokinetics, and other areas, supporting standalone or integrated projects.

1. 1上海南方模式生物科技股份有限公司 基因敲除小鼠_转基因小鼠定制modelorg.com
2. 2关于我们 上海南方模式生物科技股份有限公司modelorg.com
3. 3南模生物怎么样|专业模式生物服务|南模生物modelorg.com
4. 4如何联系|南模生物modelorg.com
5. 5Shanghai Model Organisms (China) - Wikidatawikidata.org