Shanghai Biozeron Biotechnology Co., Ltd

Shanghai Biozeron Biotechnology Co., Ltd, commonly known as Biozeron (凌恩生物), is a Shanghai-based high-tech enterprise founded in late 2014. The company specializes in applying second-generation high-throughput sequencing and third-generation single-molecule sequencing technologies to scientific research, agricultural development, and human health. Its service portfolio spans microbial diversity sequencing, metagenomics, transcriptomics, single-cell sequencing, spatial transcriptomics, proteomics, metabolomics, and genome sequencing for plants, animals, bacteria, fungi, and viruses. Biozeron has built a comprehensive omics data production line by introducing multiple sequencing platforms, including BGI's DNBSEQ-T7, DNBSEQ-G99, and DNBSEQ-E25 second-generation sequencers, the DNBelab C4-TaiM4 single-cell platform, and the Wutong nanopore sequencer from BGI's Qitan Technology, alongside its existing PacBio third-generation single-molecule sequencing platform. The company states that its services reach customers in multiple countries and regions worldwide, with over ten thousand client engagements. Key milestones include ISO quality management system certification in 2015, recognition as a Shanghai high-tech enterprise in 2017, and inclusion on Shanghai's specialized, refined, distinctive, and innovative (专精特新) enterprise list in 2021. In 2018, Biozeron partnered with the University of Illinois, the HudsonAlpha Institute for Biotechnology, and NRGene to build a large-scale complex plant and animal genome research service platform, and established Biozeron Biotechnology (Shenzhen) Co., Ltd. to focus on large complex genome projects. That same year, it formed a plant physiology joint research center with Israel's PDT company. Between 2019 and 2021, it obtained multiple AAA-grade quality service integrity certifications. Biozeron has developed numerous new research service offerings and holds 58 patents and software copyrights. Notable innovations include the HiC-Meta technology for three-dimensional metagenomics, launched in spring 2019 in collaboration with Phase Genomics, and the early domestic adoption of environmental eDNA metabarcoding sequencing in late 2019. The company continues to expand its platform capabilities, recently adding the MGI SURFseq Q series and 10x Chromium iX single-cell platform.

Shanghai Biozeron Biotechnology Co., Ltd (凌恩生物) was established in late 2014 in Shanghai as a high-tech company dedicated to applying second-generation high-throughput sequencing and third-generation single-molecule sequencing technologies to scientific research, agricultural development, and human health. From its inception, the company focused on building a comprehensive omics service platform, integrating sequencing technologies with bioinformatics analysis. In 2015, Biozeron obtained ISO quality management system certification, establishing a foundation for quality-controlled service delivery. In 2017, the company was awarded the Shanghai High-Tech Enterprise certificate, recognizing its technological capabilities and innovation potential. A significant expansion occurred in 2018 when Biozeron partnered with the University of Illinois, the HudsonAlpha Institute for Biotechnology, and NRGene, a company specializing in genome assembly technology, to jointly build a large-scale complex plant and animal genome research service platform. In the same year, it established Biozeron Biotechnology (Shenzhen) Co., Ltd. in Shenzhen, specifically targeting large and complex genome projects. Also in 2018, Biozeron and Israel's PDT company jointly founded a plant physiology joint research center. In spring 2019, Biozeron introduced HiC-Meta, described as China's first three-dimensional genomic metagenomics research project. This technology, developed in collaboration with Phase Genomics of the United States, combined three-dimensional genomics with metagenomics to overcome difficulties in genome sequencing and assembly from complex samples, improving the assembly quality of single bacterial genomes and enabling deeper exploration of species interactions in environmental and medical research. In late 2019, Biozeron became one of the first in China to carry out environmental eDNA metabarcoding sequencing. Between 2019 and 2021, the company received multiple certifications including AAA-grade quality service integrity unit. In 2021, Biozeron was included on Shanghai's specialized, refined, distinctive, and innovative (专精特新) enterprise list, highlighting its specialized expertise and innovation. Over the years, Biozeron has continuously invested in technology introduction and development. It has successfully introduced multiple sequencing platforms, including BGI's DNBSEQ-T7, DNBSEQ-G99, and DNBSEQ-E25 second-generation sequencers, the DNBelab C4-TaiM4 single-cell platform, and the Wutong nanopore sequencer from BGI's Qitan Technology. Combined with its existing PacBio third-generation single-molecule sequencing platform, the company has built a complete omics data production line covering both second- and third-generation sequencing. Its service network spans multiple countries and regions, having served over ten thousand customers. As of recent years, Biozeron has obtained 58 patents and software copyrights and developed dozens of new technology types, filling gaps in domestic research service offerings. The company continues to expand its platform capabilities, recently adding the MGI SURFseq Q series and the 10x Chromium iX single-cell platform, and remains active in providing cutting-edge multi-omics services to the scientific community.

• 2021

  Included on Shanghai's specialized, refined, distinctive, and innovative (专精特新) enterprise list.

• 2019

  Launched HiC-Meta, China's first three-dimensional genomic metagenomics research project, in collaboration with Phase Genomics; became one of the first in China to carry out environmental eDNA metabarcoding sequencing.

• 2018

  Partnered with University of Illinois, HudsonAlpha Institute for Biotechnology, and NRGene to build a large-scale complex genome research service platform; established Biozeron Biotechnology (Shenzhen) Co., Ltd.; formed plant physiology joint research center with Israel's PDT.

• 2017

  Awarded Shanghai High-Tech Enterprise certificate.

• 2015

  Obtained ISO quality management system certification.

• 2014

  Founded in late 2014 in Shanghai.

A high-tech research service provider specializing in second- and third-generation sequencing and multi-omics solutions for life sciences, agriculture, and human health.

• Microbial diversity sequencing

  High-throughput sequencing services for analyzing microbial community diversity.

• Third-generation full-length amplicon sequencing

  Full-length amplicon sequencing using third-generation platforms for higher resolution taxonomic profiling.

• Metagenomic sequencing

  Shotgun metagenomic sequencing services for comprehensive analysis of microbial communities.

• HiC-Meta

  Three-dimensional genomic metagenomics technology combining Hi-C with metagenomics to improve single bacterial genome assembly from complex samples.

• Single-cell transcriptome sequencing

  Single-cell RNA sequencing services using platforms such as DNBelab C4-TaiM4 and 10x Chromium.

• Spatial transcriptomics

  Spatial transcriptomics services including BGI Stereo-seq.

• Proteomics

  Proteomics services including Astral platform.

• Metabolomics

  Targeted and untargeted metabolomics analysis services.

• Whole genome sequencing

  Genome sequencing services for plants, animals, bacteria, fungi, and viruses.

• eDNA metabarcoding

  Environmental DNA metabarcoding services for biodiversity assessment.

1. 1上海凌恩生物科技有限公司biozeron.com
2. 2上海凌恩生物科技有限公司 - 关于我们biozeron.com
3. 3Shanghai Biozeron Biotechnology Co., Ltd (China) - Wikidatawikidata.org