RevBio
RevBio is a Massachusetts-based company developing TETRANITE®, a patented regenerative bone adhesive inspired by the sandcastle worm.
Last updated September 16, 2026
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Overview
RevBio is headquartered in Lowell, Massachusetts, and was founded in 2014 by Brian Hess. The company is developing TETRANITE®, a synthetic bone adhesive bioinspired by the sandcastle worm. TETRANITE is described as a patented biomaterial intended for bone repair across neurosurgical, orthopaedic, dental, and animal health indications, and RevBio is conducting its first-in-human clinical trial on the bone glue.
History
RevBio was founded in 2014 by Brian Hess with the goal of commercializing TETRANITE®, a regenerative bone adhesive. The company is headquartered in Lowell, Massachusetts, and is a MassChallenge start-up accelerator alum. It has won over 10 grants, received multiple patents, and is conducting its first-in-human clinical trial on its biomimetic bone glue.
Products and positioning
Developer of a patented synthetic bone adhesive platform for bone repair.
TETRANITE®
A patented synthetic bone adhesive bioinspired by the sandcastle worm, intended for bone repair in neurosurgical, orthopaedic, dental, and animal health indications.
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