PULSALYS
PULSALYS is a Lyon–Saint-Étienne deep-tech innovation incubator and accelerator that turns University of Lyon laboratory discoveries into startups and industrial partnerships.
Last updated September 27, 2026
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Overview
PULSALYS is a French technology transfer and deep-tech innovation company based in Villeurbanne, in the Lyon metropolitan area. It describes itself as an incubator and accelerator of deep-tech innovations for Lyon and Saint-Étienne, working to transform scientific discoveries from University of Lyon laboratories into economic opportunities for companies and startups. Its activity sits at the intersection of academic research, intellectual property, startup creation and industrial partnership, and it is positioned as a key player in the attractiveness and economic development of the Lyon / Saint-Étienne territory. The organisation was created in December 2013 under the French Programme d'Investissements d'Avenir (PIA) with the legal status of a Société d'Accélération du Transfert de Technologies (SATT). That status is a specific French public-policy vehicle designed to professionalise the transfer of research results from public laboratories to the market. Over the following years PULSALYS built a portfolio of funded projects, invested capital and supported startups, and it reports key figures on its website (as of 30 September 2025) covering financed projects, millions of euros invested, startups accompanied, funds raised by those startups and jobs created in them. PULSALYS supports researchers and entrepreneurs through startup-building programmes, workshops and events. Its public agenda includes startup workshops on product strategy, strategic positioning and technology roadmaps, as well as networking events such as "Meet Your DeepTech Partners". It also maintains an intellectual property function, illustrated by the arrival of a Deputy Intellectual Property Manager announced on its news feed. The company's ecosystem is visible through the startups it has incubated or accompanied. Publicly highlighted examples include Oncoshift (targeted therapies), Muodim (muography imaging, which opened its capital to BRGM Invest and IRIS Instruments), Sirius Neosight (tumour analysis, launching a clinical study with the Centre Léon Bérard), AGuIX (radiotherapy enhancement technology resuming clinical trials in the United States), Alice & Bob (quantum computing, extending its Series B with investment from NVIDIA's NVentures), Novaleum (converting fat waste into biofuels, raising €1 million), Faactopi (raising €3 million from Innovacom for a reconfigurable factory) and 3Deus Dynamics (EN 9100-certified silicone components for aerospace). PULSALYS also confirms the strength of the Lyon Saint-Étienne site in French state innovation competitions, reporting a Grand Prix i-Lab and two i-PhD laureates in the 2026 edition. Its identity is therefore that of a regional deep-tech transfer and incubation platform rather than a manufacturer of consumer products: it sells and delivers technology transfer services, incubation, acceleration, intellectual property support and access to an innovation ecosystem.
History
PULSALYS was created in December 2013 under the French Programme d'Investissements d'Avenir (PIA), with the legal status of a Société d'Accélération du Transfert de Technologies (SATT). The SATT model was designed to give French public research a professional technology-transfer operator capable of detecting inventions in laboratories, protecting them through intellectual property, maturing them and bringing them to market through licences, industrial partnerships or new companies. PULSALYS was assigned this mission for the Lyon and Saint-Étienne research and innovation site, drawing on discoveries from University of Lyon laboratories. From its base in Villeurbanne, in the Lyon metropolitan area, PULSALYS developed into what it describes as an incubator and accelerator of deep-tech innovations for Lyon and Saint-Étienne, building tomorrow's innovative products and services by turning laboratory science into economic opportunities for companies and startups. Over the years it became, in its own words, a key player in the attractiveness and economic development of the Lyon / Saint-Étienne territory. Its activity combines several functions. It finances and supports technology maturation projects, manages intellectual property, helps researchers and entrepreneurs create startups, and connects them with investors and industrial partners. Its website publishes key figures as of 30 September 2025 covering the number of financed projects, millions of euros invested, startups accompanied, funds raised by those startups and jobs created in them, reflecting the cumulative output of the model. The startups associated with PULSALYS illustrate the breadth of the deep-tech fields it covers. Oncoshift works on a new generation of targeted therapies. Muodim develops muography and opened its capital to BRGM Invest and IRIS Instruments in July 2026 to accelerate the democratisation of the technology. Sirius Neosight specialises in tumour analysis and launched a clinical study with the Centre Léon Bérard in July 2026 to predict response to cancer treatments. AGuIX, a technology combining imaging and therapy to improve radiotherapy efficacy, resumed clinical trials in the United States in June 2026. Alice & Bob, active in quantum computing, extended its Series B in May 2026 with investment from NVentures, NVIDIA's venture capital arm. Novaleum, incubated by PULSALYS and born from three Lyon research laboratories, raised €1 million in May 2026 to transform fat waste into biofuels. Faactopi raised €3 million from Innovacom in May 2026 to deploy Europe's first reconfigurable factory. 3Deus Dynamics, certified EN 9100, positioned itself as a new industrial platform for critical silicone components in aerospace. PULSALYS also plays a role in the French state innovation competitions. In September 2026 it confirmed the excellence of the Lyon Saint-Étienne site in the 2026 edition, reporting a Grand Prix i-Lab and two i-PhD laureates, following the awards ceremony held on 16 September 2026. Its public programme includes startup workshops on product strategy and de-risking, strategic positioning in the target market and technology roadmaps, as well as events such as Meet Your DeepTech Partners. It also strengthened its intellectual property team with the arrival of Céline Mathevet as Deputy Intellectual Property Manager, announced on 23 September 2026. Through these activities PULSALYS operates as a regional deep-tech transfer and incubation platform rather than a manufacturer of consumer goods.
PULSALYS is created under the Programme d'Investissements d'Avenir (PIA) with the status of Société d'Accélération du Transfert de Technologies (SATT).
Key figures published on the PULSALYS website as of 30 September 2025 cover financed projects, millions of euros invested, startups accompanied, funds raised by startups and jobs created.
Faactopi raises €3 million from Innovacom to deploy Europe's first reconfigurable factory.
Novaleum, incubated by PULSALYS and born from three Lyon research laboratories, raises €1 million to transform fat waste into biofuels.
Alice & Bob announces an extension of its Series B, including investment from NVentures, NVIDIA's venture capital arm.
Clinical trials of the AGuIX technology, combining imaging and therapy to improve radiotherapy, resume in the United States.
Sirius Neosight and the Centre Léon Bérard launch a clinical study to predict response to cancer treatments.
Muodim opens its capital to BRGM Invest and IRIS Instruments to accelerate the democratisation of muography.
PULSALYS confirms the excellence of the Lyon Saint-Étienne site in the 2026 state innovation competitions with one i-Lab Grand Prix and two i-PhD laureates.
PULSALYS announces the arrival of Céline Mathevet as Deputy Intellectual Property Manager.
Products and positioning
Regional deep-tech technology transfer, incubation and acceleration platform for the Lyon–Saint-Étienne innovation ecosystem, operating as a SATT under the French Programme d'Investissements d'Avenir.
Technology transfer services (SATT)
Detection, protection, maturation and transfer of scientific discoveries from University of Lyon laboratories to companies and startups.
Deep-tech startup incubation and acceleration
Support for researchers and entrepreneurs creating deep-tech startups in the Lyon–Saint-Étienne ecosystem.
Intellectual property support
Intellectual property function within PULSALYS, including a Deputy Intellectual Property Manager role.
Startup workshops
Workshops on product strategy and de-risking, strategic positioning in the target market and technology roadmaps.
Meet Your DeepTech Partners
Networking event listed in the PULSALYS agenda.
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