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PNA Bio

American biotechnology company producing peptide nucleic acid and CRISPR/Cas9 research reagents.

Last updated September 10, 2026

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Overview

PNA Bio Inc. is a biotechnology company headquartered in Thousand Oaks, California, that manufactures Peptide Nucleic Acid (PNA) reagents and CRISPR/Cas9 genome-editing tools for life science research. Founded in 2011, it was the sole licensed provider of PNA products for many years and, since 2013, has been recognized as the first company to commercially offer Cas9 protein to the global research community. Its two platforms — PNA chemistry and CRISPR/Cas9 — serve molecular biology, genetics, and diagnostics labs worldwide.

History

PNA Bio Inc. is a biotechnology company headquartered in Thousand Oaks, California, that manufactures Peptide Nucleic Acid (PNA) reagents and CRISPR/Cas9 genome-editing tools for life science research. Founded in 2011, PNA Bio was the sole licensed provider of PNA products for many years and, since 2013, has been recognized as the first company to commercially offer Cas9 protein to the global research community. The company's two platforms — PNA chemistry and CRISPR/Cas9 — serve molecular biology, genetics, and diagnostics labs worldwide.

Products and positioning

Leading provider of custom PNA, CRISPR/Cas9 products, and gene editing support for research, diagnostics, and beyond.

  • Custom PNA oligos

    Typically supplied at greater than 95% purity following HPLC purification, with analytical documentation that includes mass-confirmation data.

  • PNA FISH probes

    High affinity and specificity for telomeres, centromeres, and others.

  • PNA PCR blockers

    PNA can block amplification of unwanted DNA to detect SNP.

  • Cas9 protein with NLS

    Works for many model systems, guaranteed to work.

  • Custom KO/KI cell lines

    Efficient and cost effective KO and KI cell line generation.

  • sgRNA synthesis service

    High purity single guide RNA for efficient CRISPR gene editing, free design service.

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