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ParaPRO LLC

ParaPRO LLC is a U.S. specialty pharmaceutical company focused on anti-parasitic therapies for human infestations such as head lice and scabies.

Last updated September 29, 2026

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Overview

ParaPRO LLC is a specialty pharmaceutical company based in Carmel, Indiana, in the United States. It was established in 2002 with the goal of discovering and commercializing human clinical uses for the anti-parasitic compound spinosad, under an agreement with Eli Lilly. The company's mission is to bring innovative therapies to market that address the personal and public health concerns caused by infestations such as head lice and scabies, particularly in an era of widespread resistance that leads to treatment failure. ParaPRO's flagship product is Natroba™ (spinosad) Topical Suspension 0.9%, a prescription treatment for head lice. According to the company, Natroba is the most often prescribed Rx medication in its category. The active compound, spinosad, is described by ParaPRO as a naturally derived anti-parasitic agent with a unique mechanism of action and no known resistance issues. The company emphasizes a naturally superior mechanism of action and positions its therapies as uniquely targeted topical treatments. Strategically, ParaPRO focuses on innovating anti-parasitic formulations that eradicate infestations while minimizing disruption and economic burden on patients and families. It also supports the broader professional community with current insights, tools, and resources, and partners with industry organizations such as the National Association of School Nurses (NASN) and the American Academy of Family Physicians (AAFP) to improve outcomes for children and families. The company describes itself as entrepreneurially minded, accountable to customers, and passionate about advancing the quality of care for patients. ParaPRO operates primarily in the United States market. Its headquarters are in Carmel, Indiana. The company remains privately held and continues to develop and market treatments for human parasitic infestations.

History

ParaPRO LLC was established in 2002 as a specialty pharmaceutical company. Its founding purpose was to discover and commercialize human clinical uses for the anti-parasitic compound spinosad, through an agreement with Eli Lilly. This agreement provided the foundation for the company's entry into the human health market, leveraging spinosad's properties as a naturally derived anti-parasitic agent. From its base in Carmel, Indiana, ParaPRO developed its flagship product, Natroba™ (spinosad) Topical Suspension 0.9%, a prescription treatment for head lice. The company positioned Natroba as a uniquely targeted topical therapy and, according to its own statements, it became the most often prescribed Rx medication in the head lice category. ParaPRO has emphasized that spinosad has a naturally superior mechanism of action with no known resistance issues, addressing a growing concern in the treatment of head lice and scabies. Over the years, ParaPRO has focused on innovating anti-parasitic formulations that eradicate infestations while minimizing disruption and economic burden on patients and families. The company has also built partnerships with professional organizations such as the National Association of School Nurses (NASN) and the American Academy of Family Physicians (AAFP) to support education and improve outcomes for children and their families. ParaPRO describes itself as entrepreneurially minded, accountable to its customers, and passionate about advancing the quality of care for patients. As of the latest available information, ParaPRO remains a privately held company operating primarily in the United States, with its headquarters in Carmel, Indiana. It continues to develop and market therapies for human parasitic infestations.

  • 2002

    ParaPRO LLC established to discover and commercialize human clinical uses for spinosad through an agreement with Eli Lilly.

  • Natroba (spinosad) Topical Suspension 0.9% developed and marketed as a prescription treatment for head lice.

Products and positioning

Specialty pharmaceutical company focused on innovative anti-parasitic therapies for human infestations, emphasizing naturally derived compounds and patient/family-centric care.

  • Natroba (spinosad) Topical Suspension 0.9%

    Prescription topical treatment for head lice, described as the most often prescribed Rx medication in its category.

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