Open Bioinformatics Foundation
A volunteer-run nonprofit that supports open-source software, community infrastructure, and collaboration in bioinformatics.
Last updated August 26, 2026
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Overview
The Open Bioinformatics Foundation, commonly known as OBF, is an international volunteer-run nonprofit organization supporting the development and sustainability of open-source software in bioinformatics and the life sciences. It emerged in 2001 from cooperation among the BioJava, BioPerl, and BioPython projects, and subsequently became a broader umbrella for open bioinformatics communities and infrastructure. Rather than operating as a conventional commercial software company, OBF provides organizational support, shared services, events, funding assistance, and community coordination for projects whose software is generally developed and distributed under free and open-source principles. A central part of OBF's role is to help bioinformatics projects maintain the technical and social infrastructure needed for distributed collaboration. This includes hosting or supporting mailing lists, websites, and code repositories for projects such as BioJava, BioMOBY, BioPerl, BioPython, BioRuby, BioPHP, and EMBOSS. These projects cover programming-language toolkits, data and application interoperability, and sequence-analysis capabilities. By supporting multiple projects across different languages and technical approaches, the foundation helps sustain a common open-source ecosystem rather than promoting a single proprietary product. OBF also organizes developer-focused activities. Its best-known recurring event is the Bioinformatics Open Source Conference, commonly associated with the annual Intelligent Systems for Molecular Biology conference. The conference provides a venue for maintainers, contributors, and users to discuss software development, project governance, interoperability, community health, and emerging needs in computational biology. The foundation has additionally organized hackathon-style events intended to produce code, improve project coordination, and bring contributors together around shared technical problems. The organization participates in Google Summer of Code as an umbrella organization for participating bioinformatics projects. In that capacity, it can connect student contributors with established open-source communities and mentors. OBF also operates an Event Fellowship program designed to help researchers and contributors attend relevant events, either in person or online. The program places particular emphasis on improving access for people from groups that have historically been underrepresented in research and open-source communities. OBF introduced formal membership in 2005. In October 2012, it began an association with Software in the Public Interest, a United States nonprofit that assists free and open-source software projects with organizational and financial matters. Through this relationship, donations to OBF can be handled through a structure that supports United States tax-exempt charitable giving. The foundation is governed by a board of directors representing participating Bio* projects and the wider community. Publicly identified leaders have included President Peter Cock, as well as former presidents Ewan Birney and Hilmar Lapp; Steven E. Brenner has also served on the board. The available reference material does not establish a current complete leadership roster, headquarters, operating budget, or commercial revenue figures.
History
The Open Bioinformatics Foundation was established in 2001 as an outgrowth of cooperation among the BioJava, BioPerl, and BioPython projects. These projects shared a need for community coordination and a durable organizational framework for open-source development in bioinformatics. The foundation was created to support that broader ecosystem rather than to commercialize or consolidate the individual tools. During its early development, OBF's role centered on helping volunteer-led projects collaborate and maintain practical infrastructure. Its support has included services for mailing lists, project websites, and source-code repositories. The foundation's project portfolio has included BioJava, BioMOBY, BioPerl, BioPython, BioRuby, BioPHP, and EMBOSS. Together, these initiatives represent a range of programming-language toolkits, interoperability systems, and sequence-analysis software used or developed within computational biology. Formal membership was introduced in 2005, giving the organization a more defined participation model. OBF also developed a conference and event presence, most notably through the Bioinformatics Open Source Conference. The meeting is organized as a satellite event of the annual Intelligent Systems for Molecular Biology conference and focuses on the people and practices behind open bioinformatics software. Its subject matter has included development methods, project maintenance, community organization, and collaboration across software projects. The foundation later expanded its community-development activities through developer hackathons and participation in Google Summer of Code. As a Google Summer of Code umbrella organization, OBF has provided a route for students and other contributors to work with established bioinformatics projects under the guidance of mentors. It has also run an Event Fellowship program to reduce barriers to participation in relevant events. The fellowship's stated emphasis on underrepresented groups reflects an effort to broaden access to the technical and scientific communities that sustain open-source bioinformatics. In October 2012, OBF began an association with Software in the Public Interest, a United States nonprofit that supports the creation and distribution of free and open-source software. The arrangement gives OBF access to nonprofit administrative and donation-handling support, including a mechanism through which donations can receive United States 501(c)(3) tax-exempt treatment. This relationship is an important part of the foundation's organizational infrastructure because OBF relies on community participation and nonprofit support rather than a conventional commercial business model. Governance is provided by a board of directors representing Bio* projects and the wider open bioinformatics community. Publicly documented leadership has included Peter Cock as president, with Ewan Birney and Hilmar Lapp identified as former presidents. Steven E. Brenner has been listed among former board members. The reference material does not provide a complete chronology of board service, detailed financial records, a headquarters location, or a fully documented current leadership structure. OBF's continuing identity is therefore best understood as a community umbrella organization whose principal assets are its projects, contributors, events, and shared infrastructure.
- 2012
Association with Software in the Public Interest
[1]In October 2012, OBF began working with Software in the Public Interest, supporting nonprofit administration and donation processing for the foundation.
- 2005
Formal membership created
[1]OBF introduced a formal membership structure for participation in the foundation.
- 2001
Foundation established
[1]The Open Bioinformatics Foundation emerged from the BioJava, BioPerl, and BioPython projects to support open-source development in bioinformatics.
Products and positioning
A nonprofit umbrella and community infrastructure organization for open-source bioinformatics, emphasizing collaborative software development, interoperable tools, developer engagement, and broader participation in life-science computing.
Java bioinformatics toolkit
BioJava
An open-source toolkit for bioinformatics programming in Java. It is one of the projects associated with the foundation's broader Bio* community and illustrates OBF's support for language-specific libraries used to process and analyze biological data.
Perl bioinformatics toolkit
BioPerl
A Perl-based bioinformatics toolkit and one of the projects from which the foundation developed. BioPerl provides reusable software components for biological data processing and helped establish the cross-project community represented by OBF.
Python bioinformatics toolkit
BioPython
A Python toolkit for computational biology and bioinformatics. BioPython is part of the foundation's supported project ecosystem and has also been represented in OBF governance.
Ruby bioinformatics toolkit
BioRuby
An open-source bioinformatics toolkit implemented in Ruby and included among the projects supported through the OBF community and infrastructure model.
PHP bioinformatics toolkit
BioPHP
A PHP-oriented bioinformatics project included in the foundation's portfolio of community-supported open-source tools.
Bioinformatics web-service interoperability
BioMOBY
A project focused on connecting biological data and applications through web services. It represents OBF's interest in interoperability and distributed access to bioinformatics capabilities.
Sequence-analysis toolkit
EMBOSS
An open-source sequence-analysis toolkit listed among projects supported by the foundation. Its inclusion reflects OBF's support for practical software used in biological sequence research.
Developer conference
Bioinformatics Open Source Conference
OBF's annual developer-oriented conference and a satellite meeting of Intelligent Systems for Molecular Biology. It brings together contributors and users to discuss open-source bioinformatics software, project development, and community issues.
Marketing campaigns
- Google Summer of Code umbrella organization
International
OBF participates in Google Summer of Code by serving as an umbrella organization for bioinformatics-related projects, coordinating mentors and contributor projects across participating communities.
Outcome. The program provides a structured entry route for contributors to work on open-source bioinformatics software.
- Event Fellowship program
International
OBF provides financial or participation assistance for researchers and contributors attending relevant events, including online or in-person participation, with a particular focus on underrepresented groups.
Outcome. The program is intended to broaden access to open bioinformatics meetings and community activities.
Brand decisions
2012
Association with Software in the Public InterestStrategyBackground
OBF needed nonprofit organizational and donation-handling support for its open-source community activities.
Action taken
In October 2012, the foundation began an association with Software in the Public Interest, a United States nonprofit supporting free and open-source software.
Aftermath
The association enabled donation processing through a structure supporting United States 501(c)(3) tax-exempt charitable contributions.
Sources2 sources
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