Nadosei

Nadosei is a dietary supplement brand that markets a single flagship product, the Nadosei NAD+ Booster, a 5-in-1 NMN (nicotinamide mononucleotide) capsule formula positioned around healthy longevity. The brand describes itself as Japan-formulated and manufactured in the United States at a cGMP-certified facility. Its name and stated purpose derive from the Japanese phrase 健康長寿 (kenkō chōju), meaning "health and a long life," which the brand presents as the cultural question that gave rise to the company. The core product is a daily capsule supplement built on five active ingredients: 500 mg of stabilized β-NMN at 99% verified purity, 250 mg of TMG (trimethylglycine, betaine anhydrous) as a methyl donor, plus resveratrol, quercetin, and green tea extract. Nadosei frames the formula around replenishing NAD+, the coenzyme every cell uses to produce energy, citing the roughly 50% decline in NAD+ levels between age 20 and 50 and linking that decline to fatigue, sluggish recovery, cognitive drift, and slower repair. The brand states that its 500 mg NMN dose matches the higher-end clinical arm of a 2023 randomized trial published in GeroScience, and that the inclusion of TMG addresses the methyl-group depletion caused by NMN metabolism. Nadosei sells primarily through its own direct-to-consumer website, offering a 30-day supply (60 capsules) at a listed price of $74.90 per bottle, with free shipping on subscription orders, a 60-day money-back guarantee, and the ability to pause, skip, or cancel a subscription from the customer account. The product is marketed as third-party tested every batch, cGMP certified, non-GMO, and delivered in a vegan capsule with premium amber glass packaging. The brand's positioning leans heavily on Japanese healthy-longevity culture, particularly the Okinawan Blue Zone tradition, invoking concepts such as hara hachi bu (eating to 80% full), moai (lifelong social circles), and ikigai (a daily reason for being). Nadosei presents healthy longevity as a daily practice rather than a destination, and its marketing emphasizes ritual, consistency, and gentle care over occasional intensity. The website displays a 4.9-star rating from 61 verified reviews. Nadosei is characterized in public data as a dietary supplement company in the United States. It operates as a private direct-to-consumer brand with no disclosed parent company, ownership group, or executive leadership in the available evidence. Its product line is currently limited to the NAD+ Booster NMN supplement.

Nadosei is a dietary supplement brand whose identity is built around the Japanese phrase 健康長寿 (kenkō chōju), meaning "health and a long life." According to the brand's own origin narrative, the phrase was repeated throughout the childhood of the team that would go on to formulate the product — at temple, at the dinner table, at the new year — and it became the question that built the company. The brand states that it was formulated in Japan by that team and then partnered with a US cGMP-certified facility to manufacture the product. The brand's origin story is explicitly tied to Japanese healthy-longevity culture, particularly Okinawa, which it describes as the southernmost prefecture of Japan and one of the five regions in the world demographers call a Blue Zone — places where people consistently live to 100 in good health. Nadosei cites research on Okinawan elders that identified a small set of practices: hara hachi bu (eat to 80% full), moai (lifelong social circles), ikigai (a daily reason for being), and a diet rich in plants, fish, and fermented foods. The brand presents this not as a secret but as a culture, and frames healthy longevity as a daily practice rather than a destination. Nadosei's product development centers on NAD+, the molecule every cell uses to make energy. The brand states that NAD+ levels fall roughly 50% between age 20 and 50, and that this decline is linked to the most common signatures of aging: fatigue, sluggish recovery, cognitive drift, and slower repair. It positions NMN as the most direct precursor the body can convert into NAD+. The brand's science page walks through the decline curve, the restoration curve from clinical trials, the five active ingredients, and the 32 peer-reviewed studies behind the formulation. The flagship product, the Nadosei NAD+ Booster, is a 5-in-1 NMN formula containing 500 mg of stabilized β-NMN at 99% verified purity, 250 mg of TMG (betaine anhydrous) as a methyl donor, plus resveratrol, quercetin, and green tea extract. The brand states that its 500 mg NMN dose matches the higher-end clinical arm of a 2023 randomized trial published in GeroScience, which found that 60 days of NMN supplementation significantly elevated blood NAD+ and improved walking endurance in middle-aged adults. It also cites a 2003 trial published in The Journal of Nutrition showing that even modest betaine doses significantly affect methyl-donor status, supporting the inclusion of TMG to replenish the methyl groups NMN consumes during metabolism. The product is sold as 60 capsules (a 30-day supply) at a listed price of $74.90 per bottle, with free shipping on every subscription order, a 60-day money-back guarantee, and the ability to pause, skip, or cancel from the customer account at any time. Nadosei markets the product as third-party tested every batch, cGMP certified, non-GMO, and delivered in a vegan capsule with premium amber glass packaging. The website displays a 4.9-star rating from 61 verified reviews. Public data characterizes Nadosei as a dietary supplement company in the United States. The brand operates as a private direct-to-consumer business; no parent company, ownership group, founding year, or executive leadership is disclosed in the available evidence. Its product line currently consists of the single NAD+ Booster NMN supplement.

• Nadosei is characterized in public data as a dietary supplement company in the United States.

• The brand launches its flagship Nadosei NAD+ Booster, a 5-in-1 NMN supplement, sold direct-to-consumer at $74.90 per bottle.

Premium Japan-formulated, US-manufactured NMN longevity supplement sold direct-to-consumer with clinical dosing, third-party testing, and a 60-day guarantee.

• Nadosei NAD+ Booster - NMN Supplement

  A 5-in-1 NMN formula with 500 mg β-NMN (99% purity), 250 mg TMG, resveratrol, quercetin, and green tea extract. 60 capsules, 30-day supply, $74.90 per bottle. Third-party tested, cGMP certified, non-GMO, vegan capsule.

1. 1Nadosei NAD+ Boosternadosei.com
2. 2Origin: Japanese Formulation, US Manufacturing | Nadoseinadosei.com
3. 3NAD+ Booster: 5-in-1 NMN Supplement | Nadoseinadosei.com
4. 4Nadoseiwikidata.org