Metrum Research Group
Metrum Research Group is a US-based biomedical modeling and simulation consultancy that applies quantitative methods to accelerate drug development.
Last updated September 27, 2026
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Overview
Metrum Research Group (often shortened to MetrumRG) is an American scientific consultancy specializing in biomedical modeling and simulation. Established in 2004 and headquartered in Tariffville, Connecticut, the firm describes itself as a global leader in the field, providing strategic decision-making support to biopharmaceutical companies. Its stated mission is to bring a quantitative approach to drug development and to help defeat disease, particularly in areas of unmet medical need. The company's core offering is customized modeling and simulation services delivered by scientists with experience across industry, academia, and regulatory settings. Areas of focus include dose selection, quantitative systems pharmacology (QSP), development of interactive decision-making apps, quantitative due diligence, probability of technical success assessment, trial design evaluation and optimization, preparation of regulatory documents, internal design support, and comparative effectiveness. In addition to project work, Metrum offers strategic advisory solutions covering business development recommendations for in/out licensing, data-driven asset differentiation, dynamic portfolio prioritization, enterprise-wide data science strategy, technical and regulatory risk assessment, quantitative market evaluations, decision-quality frameworks, model-informed drug development guidance, and scientific advisory committee participation. Metrum also markets Metworx, a cloud-computing platform that enables quantitative scientists to run commonly used modeling tools more efficiently. Through its Open Science initiative, the company shares free courses and open-source tools to empower current and future scientists to adopt quantitative approaches. According to its website, Metrum has supported more than 200 companies across more than 900 projects. The firm positions itself at the intersection of data, science, and technology, aiming to generate insights that impact biomedical decision making. Its vision is to be a diverse, world-class team transforming biomedical decision making to improve health for all. The company is privately held and operates globally, serving biopharmaceutical clients from its Connecticut base.
History
Metrum Research Group was established in 2004, according to the company's About page. From its base in Tariffville, Connecticut, it grew into a consultancy focused on biomedical modeling and simulation, serving biopharmaceutical clients who need quantitative support for drug development decisions. The firm's early identity centered on providing high-quality scientific expertise to help clients advance drug development programs. Over time it expanded its service lines beyond core modeling and simulation into strategic advisory work, including licensing support, portfolio prioritization, and enterprise-wide data science strategy. The company reports that it has provided strategic decision making for over 200 companies across more than 900 projects. A significant development was the creation of Metworx, a cloud-computing platform designed to let quantitative scientists run commonly used modeling tools quickly and easily. This reflected Metrum's positioning at the intersection of data, science, and technology. The company also launched an Open Science initiative, offering free courses and open-source tools to share principles and methods with the broader scientific community. Metrum has continued to build a diverse team of scientists and technologists. Its leadership includes figures such as Joydeep Bhattacharyya, President of Technology Solutions, and Shazia Bakar, Vice President of Finance, alongside numerous principal scientists and group leaders in PKPD and data science. The company remains privately held and active, with a vision to transform biomedical decision making to improve health for all.
- 2004
Metrum Research Group established.
Launched Metworx cloud computing platform for quantitative scientists.
Launched Open Science initiative with free courses and open-source tools.
Products and positioning
Global leader in biomedical modeling and simulation, bringing a quantitative approach to drug development.
Modeling & Simulation Services
Customized expert modeling and simulation services covering dose selection, QSP, interactive apps, quantitative due diligence, probability of technical success, trial design, regulatory documents, and comparative effectiveness.
Strategic Advisory Solutions
Advisory services for licensing, asset differentiation, portfolio prioritization, data science strategy, risk assessment, market evaluation, decision quality frameworks, and model-informed drug development.
Metworx
Cloud computing platform enabling quantitative scientists to use commonly used tools efficiently.
Open Science
Free courses and open-source tools shared with the scientific community.
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