Mayo Clinic Hospital — Rochester
A large academic teaching hospital in Rochester, Minnesota, comprising Mayo Clinic's Saint Marys and Methodist campuses.
Last updated August 21, 2026
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Overview
Mayo Clinic Hospital — Rochester is the hospital component of Mayo Clinic's principal academic medical center in Rochester, Minnesota. The institution consists of two major hospital campuses: Saint Marys Campus and Methodist Campus. Together they provide more than 2,000 licensed beds, extensive operating-room capacity, emergency and trauma services, adult and pediatric specialty care, cancer treatment, proton-beam therapy, psychiatric and psychological services, and highly specialized referral medicine. The hospital's institutional history reaches back to Saint Marys Hospital, founded in 1889 by the Sisters of Saint Francis of Rochester under the leadership of Mother Alfred Moes. The Franciscan community's involvement remains visible in the names of several buildings on the Saint Marys Campus. Rochester Methodist Hospital developed as the other major hospital campus associated with Mayo Clinic. In January 2014, Saint Marys and Rochester Methodist were consolidated under the single Mayo Clinic Hospital — Rochester name, while continuing to operate as distinct campuses with complementary capabilities. Saint Marys Campus has 1,265 licensed beds and 64 operating rooms. It includes the Mayo Eugenio Litta Children's Hospital, a 148-bed pediatric facility serving patients from infancy through young adulthood, as well as a large emergency department, intensive-care services, trauma and surgical units, hybrid operating rooms, and the Mayo Clinic Psychiatry and Psychology Treatment Center. Saint Marys is a Level I trauma center and stroke center and serves as the base for regional trauma coordination in southern Minnesota. Its emergency and referral network reaches beyond the local area through ground and air medical transport. Methodist Campus has 794 licensed beds and 51 operating rooms. It includes the Richard O. Jacobson Building, which houses Mayo Clinic's proton beam therapy program. The two campuses function within Mayo Clinic's integrated model, linking hospital care with outpatient medicine, medical education, biomedical research, and highly specialized consultation. The hospital is therefore not simply a local inpatient facility; it is a destination center for complex cases referred from Minnesota, neighboring states, elsewhere in the United States, and international markets. Mayo Clinic Hospital — Rochester has received prominent national recognition through Mayo Clinic's Rochester rankings. U.S. News & World Report placed Mayo Clinic, Rochester, at the top of its overall U.S. hospital rankings in 2016–17 and again in 2019–20. The hospital's identity is closely tied to Mayo Clinic's broader reputation for multidisciplinary practice, specialty depth, clinical research, and coordinated care. Its pediatric, trauma, cancer, surgical, neurological, cardiovascular, emergency, and critical-care services are delivered as parts of that larger clinical and academic system.
History
The history of Mayo Clinic Hospital — Rochester is rooted in the development of two major hospital campuses serving Mayo Clinic's medical practice. Saint Marys Hospital was established in 1889 by the Sisters of Saint Francis of Rochester, Minnesota. Mother Alfred Moes led the founding effort, and the Franciscan sisters continued to influence the hospital's administration and identity for many decades. Several Saint Marys buildings commemorate Mother Alfred and former Franciscan administrators, reflecting the campus's religious and civic origins. Saint Marys became an important hospital in Rochester's expanding medical community and ultimately formed part of Mayo Clinic's integrated academic medical center. Its modern campus developed extensive inpatient, surgical, emergency, critical-care, pediatric, psychiatric, and trauma capabilities. The campus also became associated with a major regional emergency referral network, serving local residents while receiving patients from southern and central Minnesota, northern Iowa, western Wisconsin, and more distant locations through medical transport services. The pediatric function of Saint Marys expanded significantly with the opening of Mayo Eugenio Litta Children's Hospital in 1996. Named for Eugenio Litta, a 14-year-old patient who died from a ruptured appendix, the facility was created to provide coordinated pediatric and adolescent care. It became part of Mayo Clinic's broader Children's Center, which brings together providers across more than 40 medical and surgical specialties. Rochester Methodist Hospital developed as the second major hospital campus within Mayo Clinic's Rochester operations. Methodist Campus offers broad inpatient and surgical capacity and includes the Richard O. Jacobson Building, home to the institution's proton beam therapy program. Its clinical role complements Saint Marys, which has a major emergency and trauma profile but does not operate an obstetrics department; Methodist has obstetric services but does not operate an emergency department. In January 2014, Saint Marys and Rochester Methodist were consolidated under the Mayo Clinic Hospital — Rochester name. The consolidation created a unified hospital identity while preserving the two-campus structure. Saint Marys Campus is described as having 1,265 licensed beds and 64 operating rooms, while Methodist Campus has 794 licensed beds and 51 operating rooms. The combined organization consequently has more than 2,000 licensed beds and serves as a core inpatient platform for Mayo Clinic's clinical, teaching, and research activities. The hospital's later history has been shaped by its role as a destination center for complex care. Its Saint Marys facilities include a Level I trauma center, stroke-center services, a large emergency department, pediatric emergency capability, hybrid operating rooms, and extensive intensive-care capacity. The Methodist Campus contributes additional specialty and procedural services, including proton beam therapy. Mayo Clinic's Rochester practice has repeatedly appeared at or near the top of national hospital rankings, including first place in the 2016–17 and 2019–20 U.S. News & World Report assessments. These rankings reinforced the hospital's positioning as a comprehensive academic referral institution rather than a conventional community hospital.
- 2019
Mayo Clinic Rochester again ranked first nationally
[1]Mayo Clinic, Rochester again received the top overall U.S. hospital ranking for 2019–20.
- 2016
Mayo Clinic Rochester ranked first nationally
[1]Mayo Clinic, Rochester was ranked the top overall hospital in the 2016–17 U.S. News & World Report assessment.
- 2014
Two hospital campuses consolidated
[1]Saint Marys and Rochester Methodist were brought together under the Mayo Clinic Hospital — Rochester name.
- 1996
Mayo Eugenio Litta Children's Hospital opens
[1]A 148-bed pediatric hospital opened on the Saint Marys Campus to provide multidisciplinary care for infants, children, adolescents, and young adults.
- 1889
Saint Marys Hospital founded
[1]The Sisters of Saint Francis of Rochester, led by Mother Alfred Moes, founded Saint Marys Hospital in Rochester, Minnesota.
Products and positioning
A globally recognized academic referral hospital positioned around multidisciplinary specialty care, complex-case treatment, clinical education, and medical research within the Mayo Clinic system.
Hospital campus · 1889
Saint Marys Campus
The 1,265-bed Saint Marys Campus provides major inpatient, surgical, emergency, trauma, stroke, intensive-care, psychiatric, pediatric, and referral services. It has 64 operating rooms and includes a large emergency department, specialized trauma and surgical intensive-care units, hybrid operating rooms, and the Mayo Eugenio Litta Children's Hospital.
Pediatric hospital · 1996
Mayo Eugenio Litta Children's Hospital
This 148-bed pediatric facility on the Saint Marys Campus provides multidisciplinary care for patients from birth through young adulthood. It draws on Mayo Clinic providers across more than 40 medical and surgical specialties and is part of the Mayo Clinic Children's Center.
Hospital campus
Methodist Campus
The 794-bed Methodist Campus has 51 operating rooms and provides inpatient, surgical, obstetric, and specialty care. The campus includes the Richard O. Jacobson Building, which houses Mayo Clinic's proton beam therapy program.
Acute care service
Emergency and trauma services
Saint Marys operates a large emergency department and a Level I trauma center, with adult and pediatric trauma capability, intensive-care support, psychiatric treatment spaces, observation services, and regional referral links supported by ground and air medical transport.
Cancer treatment
Proton beam therapy
The proton beam therapy program at the Richard O. Jacobson Building on Methodist Campus provides a specialized radiation-treatment modality within Mayo Clinic's cancer-care system.
Brand decisions
2014
Consolidation of Saint Marys and Rochester MethodistStrategyBackground
Mayo Clinic operated two major hospital campuses in Rochester with complementary services and separate historical identities.
Action taken
The Saint Marys and Rochester Methodist operations were consolidated under the Mayo Clinic Hospital — Rochester name while continuing to function across the Saint Marys and Methodist campuses.
Aftermath
The unified hospital structure aligned the two campuses within a single Mayo Clinic hospital identity and preserved their differentiated emergency, obstetric, surgical, pediatric, and specialty capabilities.
Recent events
- 2019
Mayo Clinic, Rochester again ranked first nationally[1]
Other
Mayo Clinic, Rochester received the number-one overall position in the 2019–20 U.S. News & World Report hospital rankings.
- 2016
Mayo Clinic, Rochester ranked first in the United States[1]
Other
U.S. News & World Report ranked Mayo Clinic in Rochester as the leading overall hospital in its 2016–17 national assessment, citing broad performance across multiple specialties and procedures.
- 2014
Saint Marys and Rochester Methodist consolidated under one hospital name[1]
M&A
The Saint Marys and Rochester Methodist hospital operations were consolidated under the Mayo Clinic Hospital — Rochester name, with the two campuses retaining different clinical facilities and functions.
Sources2 sources
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