Kyoto Monotech Co., Ltd.

Kyoto Monotech Co., Ltd. (株式会社京都モノテック) is a Japanese specialist company based in Kyoto that develops, manufactures, and sells separation media and columns for liquid chromatography, together with DNA purification kits and antibody purification kits and columns. The company was established on 24 January 2001 and is led by representative director Hiroyoshi Minakuchi, who holds a doctorate in engineering from Kyoto University. Its stated business scope covers the development, manufacture, and sale of liquid chromatography columns, DNA purification kits, antibody purification kits and columns, and various separation media. The company's product identity is built around monolithic silica technology. Its Monobis and MonoCap capillary column lines, the UniFlow series of capillary LC columns, and the Ex-Pure product family are aimed at analytical and life-science users who need high separation performance with low solvent consumption. In 2026 the company introduced a UniFlow capillary column with an inner diameter of 20 micrometres, formed by applying its monolith silica molding technology inside an ultra-fine capillary, and launched UniFlow Symmetry, a dedicated end fitting for monolithic capillary columns designed to eliminate dead volume. It also introduced the Lenitas 1.9 packed emitter column, an all-in-one capillary column with an emitter formed directly at the column outlet, and UniFlow Core, a next-generation capillary LC column using a continuous porous structure. Kyoto Monotech serves the analytical instrumentation and biopharmaceutical research supply chain rather than end consumers. Its customers are laboratories, analytical testing services, and biopharmaceutical developers, and the company also offers contracted analytical testing services. Product announcements on its website show an active development pipeline, with new capillary column sizes, dedicated fittings, and emitter columns appearing through 2025 and 2026, alongside price revisions and the discontinuation of the MonoTip product line because of difficulty obtaining certain components. The company remains a privately held Japanese corporation with stated capital of 20,000 thousand yen. Its headquarters are in Kyoto's Kita ward, with a business office address in Kamigyo ward, Kyoto. It maintains a Japanese-language website with an English section, a staff blog, and links to related antibody business and industry consortium activities.

Kyoto Monotech Co., Ltd. was established on 24 January 2001 in Kyoto, Japan. The company was founded around monolithic silica separation technology, a field in which its representative director, Hiroyoshi Minakuchi, holds a doctorate in engineering from Kyoto University. From the outset the business was defined as the development, manufacture, and sale of liquid chromatography columns, DNA purification kits, antibody purification kits and columns, and various separation media. The company's early and continuing product identity rests on monolithic silica capillary columns, marketed under names such as Monobis and MonoCap. These columns use a continuous porous silica structure rather than packed particles, a design that allows high separation performance at lower backpressure and with reduced solvent consumption. Over time Kyoto Monotech expanded the Monobis capillary column range with additional inner diameters and customer-specified lengths, and built out related product families including Ex-Pure columns and antibody purification columns and cartridges. In the mid-2020s the company continued to release new capillary LC products. In March 2026 it launched UniFlow Core, a next-generation capillary LC column using a continuous porous structure that combines low pressure, high separation, and high-speed separation. Later that month it introduced the Lenitas 1.9 packed emitter column, an all-in-one capillary column with an emitter formed directly at the column outlet. In April 2026 it released UniFlow Symmetry, a dedicated end fitting for monolithic capillary columns designed to eliminate dead volume and prevent peak tailing. In August 2026 it added a 20 µm inner-diameter capillary to the UniFlow series, applying its monolith molding technology inside an ultra-fine capillary to enable higher-resolution analysis with less solvent. The company has also adjusted its portfolio in response to supply conditions. In June 2025 it discontinued the MonoTip product line, including MonoTip C18, MonoTip Trypsin, and MonoTip TiO, because some components became difficult to obtain. It has periodically revised prices for products such as Ex-Pure and the MonoBis Guard column, citing rising raw material costs and other circumstances. Alongside product sales, Kyoto Monotech offers contracted analytical testing services and maintains technical information, a staff blog, and links to antibody-related business and industry consortium activities on its website. The company remains privately held with stated capital of 20,000 thousand yen, headquartered in Kyoto's Kita ward with a business office in Kamigyo ward.

• Kyoto Monotech Co., Ltd. established in Kyoto, Japan.

• Site map and related functions added to the company website.

• Price revision announced for the MonoBis Guard column.

• Discontinuation of the MonoTip product line announced due to component procurement difficulties.

• New 0.05 mm and 0.03 mm inner-diameter sizes added to the Monobis Capillary Column line, with customer-specified lengths up to 2000 mm.

• Price revision announced for Ex-Pure-related products.

• UniFlow Core next-generation capillary LC column launched.

• Lenitas 1.9 packed emitter column launched.

• UniFlow Symmetry dedicated end fitting for monolithic capillary columns launched.

• 20 µm inner-diameter capillary added to the UniFlow series.

Specialist supplier of monolithic silica capillary columns and separation media for analytical and life-science laboratories, emphasizing high separation performance with low solvent consumption.

• Monobis Capillary Column

  Monolithic silica capillary columns available in multiple inner diameters (0.1 mm, 0.075 mm, 0.05 mm, 0.03 mm) and cut to customer-specified lengths up to 2000 mm.

• MonoBis Guard column

  Guard column for the Monobis line; price revised in March 2025.

• UniFlow Core

  Next-generation capillary LC column using a continuous porous structure, achieving low pressure, high separation, and high-speed separation simultaneously.

• UniFlow Symmetry

  Dedicated end fitting for monolithic capillary columns, designed for easy and reliable connection while eliminating dead volume and preventing peak tailing.

• UniFlow series 20 µm capillary

  Ultra-fine capillary with 20 µm inner diameter containing monolithic silica, enabling higher-resolution analysis with less solvent.

• Lenitas 1.9 packed emitter column

  All-in-one capillary column with an emitter formed directly at the column outlet.

• Ex-Pure columns

  Product family for which prices were revised in July 2025 due to rising raw material costs.

• MonoTip product line

  Including MonoTip C18, MonoTip Trypsin, and MonoTip TiO; production discontinued in June 2025 due to component procurement difficulties.

• DNA purification kits

  Developed, manufactured, and sold by the company.

• Antibody purification kits and columns

  Developed, manufactured, and sold by the company.

1. 1京都モノテック-TOPk-monotech.co.jp
2. 2京都モノテック-会社情報k-monotech.co.jp
3. 3Kyoto Monotech Co., Ltd. (Japan) - Wikidatawikidata.org