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Keros Therapeutics

Keros Therapeutics is a Lexington, Massachusetts-based company developing therapeutics that modulate transforming growth factor-beta (TGF-β) signaling.

Last updated September 16, 2026

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Overview

Keros Therapeutics is a company based in Lexington, Massachusetts, whose mission is to deliver clinical benefit to patients with disorders linked to dysfunctional signaling of the transforming growth factor-beta (TGF-β) family of proteins. It focuses on differentiated product candidates designed to alter TGF-β signaling, targeting pathways critical for the growth, repair and maintenance of blood cells and tissues including bone, skeletal muscle, adipose and heart tissue. Its pipeline includes KER-065, being developed for neuromuscular diseases, and elritercept, being developed to treat ineffective hematopoiesis in myelodysplastic syndromes and myelofibrosis.

History

Keros Therapeutics is a company based in Lexington, Massachusetts. Its mission is to deliver significant clinical benefit to patients with disorders linked to dysfunctional signaling of the transforming growth factor-beta (TGF-β) family of proteins. The company focuses on developing differentiated product candidates designed to alter TGF-β signaling, targeting pathways critical for the growth, repair and maintenance of blood cells and tissues including bone, skeletal muscle, adipose and heart tissue. Its pipeline includes KER-065 for neuromuscular diseases and elritercept for ineffective hematopoiesis in myelodysplastic syndromes and myelofibrosis.

Products and positioning

Developing and commercializing novel therapeutics with the ability to modulate TGF-β signaling and unlock potentially disease-modifying benefits for patients.

  • KER-065

    Being developed for the treatment of neuromuscular diseases.

  • Elritercept

    Being developed to treat ineffective hematopoiesis in both myelodysplastic syndromes and myelofibrosis.

Recent events

  • Alon Lazarus to step down from Keros Therapeutics board[6]

    Reported:

    Keros Therapeutics announced that Alon Lazarus would be stepping down as a director, concurrent with Mary Ann Gray joining the board.

  • Keros Therapeutics appoints Keith Regnante as CFO[7]

    Reported:

    Keros Therapeutics announced the appointment of Keith Regnante as its Chief Financial Officer. He will lead financial and information technology operations and oversee investor relations and fundraising efforts.

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