Karius, Inc.
Karius is a clinical metagenomics company using genomics and AI to advance infectious disease diagnostics.
Last updated September 15, 2026
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Overview
Karius, Inc. is a clinical metagenomics company focused on elevating patient care through microbial insights. Founded in 2014 and built on intellectual property developed at Stanford University, it is headquartered in Redwood City, California, and operates a CLIA-certified, CAP-accredited, and ISO 15189-accredited laboratory for high-complexity clinical laboratory testing. The company uses genomics and AI to detect microbial cell-free DNA (mcfDNA) circulating in the body, aiming to give providers rapid and comprehensive detection of pathogens behind life-threatening infections when conventional testing falls short. Its offerings include Karius Spectrum, a blood test leveraging plasma metagenomic sequencing of mcfDNA to detect over 1,000 fungi, bacteria, DNA viruses, and parasites associated with deep-seated and difficult-to-diagnose systemic infections, and Karius Focus | BAL, a bronchoalveolar lavage fluid-based mcfDNA metagenomic sequencing test designed for detection and classification of over 500 pathogens associated with lung infection. Karius metagenomic testing solutions are being utilized by 600+ leading hospitals and transplant centers throughout the US, with over 100,000 patient samples tested.
History
Karius was founded in 2014 and is built on intellectual property developed at Stanford University. Headquartered in Redwood City, California, the company operates a CLIA-certified, CAP-accredited, and ISO 15189-accredited laboratory to perform high-complexity clinical laboratory testing. Karius metagenomic testing solutions are being utilized by 600+ leading hospitals and transplant centers throughout the US and over 100,000 patient samples tested.
Products and positioning
A leader in metagenomic sequencing for infectious disease, delivering unprecedented diagnostic insight through genomics and AI.
Karius Spectrum
A blood test leveraging plasma metagenomic sequencing of microbial cell-free DNA to detect over 1,000 fungi, bacteria, DNA viruses, and parasites associated with deep-seated and difficult-to-diagnose systemic infections.
Karius Focus | BAL
A bronchoalveolar lavage fluid-based mcfDNA metagenomic sequencing test designed for detection and classification of over 500 pathogens associated with lung infection.
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