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CTL Europe GmbH

CTL Europe GmbH is the German-based European arm of Cellular Technology Limited (CTL), the company behind the ImmunoSpot® platform for ELISPOT/FluoroSpot immune monitoring.

Last updated September 26, 2026

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Overview

CTL Europe GmbH is the European corporate entity of Cellular Technology Limited (CTL), a privately held, family owned biotechnology company whose flagship platform is ImmunoSpot®. CTL describes itself as the home of ImmunoSpot® and as the only company that, for over 25 years, has focused on advancing all aspects of immune monitoring by ELISPOT/FluoroSpot. The parent company is headquartered in Shaker Heights, a suburb of Cleveland, Ohio, and operates locations and distributors worldwide; CTL Europe GmbH serves as the European-facing arm of that organization, with its own web presence at immunospot.eu. The ImmunoSpot® portfolio spans the full workflow of cell-based immune monitoring. It includes analyzers and software for high-content ELISPOT/FluoroSpot plate reading and analysis, test kits and reagents, and a library of cryopreserved peripheral blood mononuclear cells (ePBMC). CTL also provides contract research organization (CRO) services, including plate scanning and analysis through its ScAnalysis™ service, which lets scientists without an ImmunoSpot® Analyzer ship plates to CTL for scanning, analysis, and consultation. Additional services include ELISPOT/FluoroSpot consultation, workshops, and proficiency testing. CTL was founded as a spinoff of Case Western Reserve University by Prof. Paul V. Lehmann and scientists working with him, with the intent of helping fellow scientists in their immune monitoring efforts. The company maintains an active immune-monitoring-focused research program and, according to its own company page, employs around 180 full-time staff, including 14 M.D./Ph.D.-level scientists. It is family owned and privately held, and frames its mission as helping the medical field progress by improving cell-based immune monitoring, thereby enabling basic immunological research, regulated clinical trials, and eventually clinical diagnostics. CTL Europe GmbH is active in the European market, promoting ImmunoSpot® products and services at regional scientific meetings such as CITIM in Bucharest, CIMT in Mainz, SLAS in Hamburg, IUIS in Vienna, and the World Vaccine Conference Europe in Amsterdam. Its product line continues to expand, with newer offerings such as B cell ferret ELISPOT/FluoroSpot kits and anti-ferret Ig monoclonal antibodies, and the BioSpot™ Software Suite for image analysis of viral plaque assays, micro-neutralizations, and colony counting.

History

Cellular Technology Limited (CTL), the parent of CTL Europe GmbH, was founded as a spinoff of Case Western Reserve University by Prof. Paul V. Lehmann and scientists working with him. The founders' intent was to help fellow scientists in their immune monitoring efforts, and the company has since focused on advancing all aspects of immune monitoring by ELISPOT/FluoroSpot, collectively branded ImmunoSpot®. CTL states that it is the only company that, for over 25 years, has focused on advancing all aspects of this field. From its headquarters in Shaker Heights, Ohio, CTL grew into a global biotechnology company with locations and distributors worldwide. It maintains an active immune-monitoring-focused research program and, according to its company page, employs around 180 full-time staff, including 14 M.D./Ph.D.-level scientists. The company is family owned and privately held, describing itself as dedicated to a mission rather than focused on profits. CTL Europe GmbH represents the company's European presence, operating under the ImmunoSpot® brand with a dedicated European website. Through this entity, CTL markets its analyzers, software, kits, reagents, and services across Europe and participates in regional scientific conferences. The ImmunoSpot® portfolio has expanded over time to include not only core T cell ELISPOT/FluoroSpot offerings but also B cell assays, an ePBMC library, and the BioSpot™ Software Suite for viral plaque assays, micro-neutralizations, and colony counting. Newer products include B cell ferret ELISPOT/FluoroSpot kits and anti-ferret Ig monoclonal antibodies.

  • CTL founded as a spinoff of Case Western Reserve University by Prof. Paul V. Lehmann and colleagues

  • ImmunoSpot® platform established for ELISPOT/FluoroSpot immune monitoring

  • CTL Europe GmbH active as European entity with website immunospot.eu

  • BioSpot™ Software Suite released for viral plaque assays, micro-neutralizations, and colony counting

  • B cell Ferret ELISPOT/FluoroSpot kits and anti-ferret Ig monoclonal antibodies introduced

Products and positioning

Specialist provider of end-to-end ELISPOT/FluoroSpot immune monitoring solutions — analyzers, software, kits, reagents, and CRO services — for academic and regulated research communities.

  • ImmunoSpot® Analyzers

    Hardware for high-content ELISPOT/FluoroSpot plate scanning and analysis.

  • ImmunoSpot® Software

    Software for scientifically validated ImmunoSpot® data analysis, suited to academic and regulated research.

  • ELISPOT/FluoroSpot Kits & Components

    Test kits and accessory products optimized and batch tested for ELISPOT/FluoroSpot performance.

  • ePBMC Library

    Library of cryopreserved peripheral blood mononuclear cells for immune monitoring.

  • ScAnalysis™ Service

    Plate scanning and analysis service where customers ship plates to CTL for scanning on an ImmunoSpot® Reader and analysis by trained staff.

  • BioSpot™ Software Suite

    Image-analysis software for viral plaque assays, micro-neutralizations, and colony counting.

  • B cell Ferret ELISPOT/FluoroSpot kits

    Kits and anti-ferret Ig monoclonal antibodies for ferret B cell immune monitoring.

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