CROSS Research SA
CROSS Research SA is a private Swiss contract research organization operating under the CROss Alliance® brand, specializing in early-phase clinical pharmacology and Phase I trials.
Last updated September 26, 2026
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Overview
CROSS Research SA is a private Swiss contract research organization (CRO) that operates under the registered trade name CROss Alliance®. Based in Mendrisio in the canton of Ticino, the company provides clinical development services for drugs, medical devices and nutraceuticals, with a particular focus on early clinical phase development and Phase I clinical pharmacology studies. Its client base spans start-up biotechnology companies, small and medium-sized pharmaceutical firms, and larger multinational pharmaceutical industries. The CROss Alliance® story began in 1995, when Innopharma Srl was established in Italy as the first company under the brand name. CROSS SA followed in Switzerland in 1996, and CROSS Research SA was established in 1997. The group's mission was, and remains, to accompany emerging biotech and medium-sized pharmaceutical companies through the early clinical development of new potential drugs. Over more than two decades the group expanded its services and quality, becoming what it describes as a firmly established niche CRO in the clinical trial arena. In 2011, CROSS Metrics SA was established to provide full-service data management and statistics. CROss Alliance® offers highly tailored services covering overall project development and consultancy, bioequivalence and bioavailability studies, cardiac safety, central nervous system, dermatology and gastroenterology, among other clinical areas. The team reports a portfolio of more than 500 clinical studies performed in healthy volunteers and patients, and around 30 years of activity in clinical pharmacology. Studies can be conducted in the company's Phase I Unit in Switzerland or in the Phase I Unit of the Clinical Pharmacology Department of Vienna Medical University, while Phase II/III studies are supported through selected clinical sites with high medical specialization and GCP compliance. The company is headquartered at Via Luigi Lavizzari 18 in Somazzo, Salorino, Mendrisio, with an additional site at Via Francesco Antonio Giorgioli 14 in Arzo, Mendrisio. It positions itself as a profit-oriented organization that places subject and patient health first, emphasizing win-win cooperation with clients. CROss Alliance® is a registered trade name for CROSS Research SA.
History
The CROss Alliance® group traces its origins to 1995, when Innopharma Srl was established in Italy as the first company to be created under the brand name CROss Alliance®. The following year, in 1996, CROSS SA was established in Switzerland, and in 1997 CROSS Research SA was founded. From the outset, the group's mission was to accompany emerging biotechnology companies and medium-sized pharmaceutical companies in the early clinical development of new potential drugs. After the implementation of the European Economic Area in January 2002, the group noted that Switzerland, although formally outside the new economic area, found itself at the centre of what it describes as a European Renaissance, participating due to geographical and historical reasons and thanks to its specific competences in the pharmaceutical field. This scenario gave Swiss companies, especially those able to cooperate with the new surrounding reality, a strong opportunity to grow. Driven by the need for highly specialized services in clinical development, CROSS Metrics SA was established in 2011 to provide a full service in data management and statistics. Over more than two decades, the CROss Alliance® group navigated positive and more complex periods, including the global economic crisis, and grew, evolved and increased its services and quality, becoming a firmly established niche CRO in the clinical trial arena. Today, CROss Alliance® provides tailored services to a large number of pharmaceutical companies, building highly motivated relationships that support continuous growth. The organization reports around 30 years of activity in clinical pharmacology and a portfolio of more than 500 clinical studies performed in healthy volunteers and patients. Its services cover overall project development and consultancy, Phase I studies conducted in its Swiss Phase I Unit or in the Phase I Unit of the Clinical Pharmacology Department of Vienna Medical University, and Phase II/III studies supported through selected clinical sites with high medical specialization and GCP compliance. The company remains a private Swiss CRO headquartered in Mendrisio, Ticino.
- 2026
CROss Alliance® shares a technology update and joins the 33rd National GIQAR Congress.
- 2011
CROSS Metrics SA established to provide full-service data management and statistics.
- 1997
CROSS Research SA established in Switzerland.
- 1996
CROSS SA established in Switzerland.
- 1995
Innopharma Srl established in Italy as the first company under the CROss Alliance® brand name.
Products and positioning
A niche contract research organization focused on early clinical phase development and Phase I clinical pharmacology, offering highly tailored services to biotech, mid-size and large pharmaceutical clients.
Phase I clinical trials
Early clinical phase studies conducted in healthy volunteers and patients.
Bioequivalence and bioavailability studies
Studies supporting generic drugs and formulations.
Cardiac safety studies
Clinical pharmacology studies assessing cardiac safety.
Central nervous system studies
Clinical studies in the CNS therapeutic area.
Dermatology studies
Clinical studies in dermatology.
Gastroenterology studies
Clinical studies in gastroenterology.
Data management and statistics
Full-service data management and statistics provided by CROSS Metrics SA.
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