Chromosome Science Labo Inc.

Chromosome Science Labo Inc. (有限会社クロモソームサイエンスラボ) is a Japanese life-science service company based in Shiroishi-ku, Sapporo, Hokkaido. It was established on 20 January 2004 as a Hokkaido University-originated venture, with the stated purpose of making the chromosome analysis techniques developed in the university's animal chromosome laboratory available to a wider community of researchers. The company is led by Representative Director Masahisa Tsuji and has technical advisor Yoichi Matsuda, a professor at Nagoya University's Graduate School of Bioagricultural Sciences. Its head office is in Kikusui, Shiroishi-ku, Sapporo, with a separate laboratory in Higashi-Sapporo, also in Shiroishi-ku. The core business is commissioned (contract) analysis using fluorescence in situ hybridization (FISH) and related chromosome analysis methods, together with gene testing and guidance in those techniques. The company handles a wide range of sample types, from chromosome preparations to frozen and paraffin-embedded tissue sections, and supports many animal species beyond human and mouse — including rodents such as rat and hamster, birds such as chicken and Japanese quail, and reptiles such as Japanese rat snake and soft-shelled turtle. Alongside the service business, the group manufactures and sells research reagents, notably custom FISH probes and X/Y chromosome FISH probes, through the affiliated company Chromo Science Co., Ltd. (株式会社クロモサイエンス), founded on 11 March 2010. Chromosome Science Labo positions itself as a specialist technical partner for academic and corporate research laboratories rather than a general diagnostics provider. Its published client list includes Hokkaido University, Asahikawa Medical University, the University of Tokyo, the National Defense Medical College, the University of Tsukuba, RIKEN, Osaka University, Kyoto University, Yamaguchi University, Kumamoto University, Funakoshi Co., Ltd., Takeda Pharmaceutical Company, and Taiho Pharmaceutical. It also exhibits at scientific conferences, such as the 24th Annual Meeting of the Japanese Society for Regenerative Medicine held at Pacifico Yokohama in March 2025. The company remains a small, privately held venture with stated capital of 3 million yen for the service company and 20 million yen for the reagent affiliate.

Chromosome Science Labo Inc. was founded on 20 January 2004 in Sapporo, Hokkaido, as a venture company originating from Hokkaido University. Its founding purpose, as stated on its website, was to make the chromosome analysis technologies held by the university's Faculty of Science animal chromosome laboratory available to a broad community of researchers. The company was established as a yugen kaisha (limited company) with stated capital of 3 million yen, led by Representative Director Masahisa Tsuji, and it maintains a technical advisor relationship with Yoichi Matsuda, a professor at Nagoya University's Graduate School of Bioagricultural Sciences. From its base in Shiroishi-ku, Sapporo, the company built a contract analysis business around FISH (fluorescence in situ hybridization) and chromosome analysis. Over time it broadened the range of sample types it accepts — from chromosome preparations to frozen sections and paraffin-embedded tissue sections — and the range of species it can handle, including human and mouse, rodents such as rat and hamster, birds such as chicken and Japanese quail, and reptiles such as the Japanese rat snake and soft-shelled turtle. The company describes ongoing research and development to accumulate further techniques and respond to a widening set of client requests. On 11 March 2010, an affiliated company, Chromo Science Co., Ltd. (株式会社クロモサイエンス), was established with stated capital of 20 million yen, also led by Masahisa Tsuji. This affiliate handles the manufacture and sale of research reagents — notably FISH probes — and also accepts FISH analysis commissions, complementing the service business of the original company. Both entities share the same head office address in Kikusui, Shiroishi-ku, and the same laboratory address in Higashi-Sapporo, Shiroishi-ku, and both bank with the Hokuyo Bank Minamigo-dori branch. The group's client base has included major Japanese universities and research institutes — Hokkaido University, Asahikawa Medical University, the University of Tokyo, the National Defense Medical College, the University of Tsukuba, RIKEN, Osaka University, Kyoto University, Yamaguchi University, and Kumamoto University — as well as reagent distributor Funakoshi Co., Ltd. and pharmaceutical companies Takeda Pharmaceutical Company and Taiho Pharmaceutical. The company continues to promote its services at scientific meetings, announcing an exhibition booth at the 24th Annual Meeting of the Japanese Society for Regenerative Medicine, held at Pacifico Yokohama from 20 to 22 March 2025. It remains a small, privately held specialist venture, publishing periodic notices about summer and year-end holiday closures and the resulting limits on sample acceptance.

• Chromosome Science Labo Inc. founded in Sapporo, Hokkaido, as a Hokkaido University-originated venture; stated capital 3 million yen; Masahisa Tsuji as Representative Director.

• Affiliated company Chromo Science Co., Ltd. (株式会社クロモサイエンス) established for manufacture and sale of research reagents, including FISH probes; stated capital 20 million yen.

• Published summer holiday notice (August 10-18, 2024) with sample acceptance limits.

• Announced exhibition at the 24th Annual Meeting of the Japanese Society for Regenerative Medicine (March 20-22, 2025, Pacifico Yokohama).

• Published summer holiday notice (August 9-17, 2025); new sample acceptance from August 18.

• Published summer holiday notice (August 8-16, 2026); new sample acceptance from August 17.

Specialist contract research and reagent supplier for chromosome and FISH analysis, originating from Hokkaido University and serving academic and pharmaceutical research laboratories in Japan.

• FISH analysis contract service

  Commissioned analysis of genes and chromosomes using fluorescence in situ hybridization, covering chromosome preparations through frozen and paraffin-embedded tissue sections.

• Chromosome analysis contract service

  Chromosome-based analysis supporting a wide range of animal species including human, mouse, rat, hamster, chicken, Japanese quail, Japanese rat snake, and soft-shelled turtle.

• Custom FISH probes

  Manufacture and sale of chromosome probes and related reagents used in FISH, handled by affiliate Chromo Science Co., Ltd.

• X/Y chromosome FISH probes

  FISH probes for X and Y chromosome detection offered by the group.

• FISH protocols

  Published protocols for preparing samples for shipment and other FISH procedures.

• Gene testing and technical guidance

  Gene testing services and instruction in chromosome analysis and gene testing techniques.

1. 1染色体解析・FISH解析／有限会社クロモソームサイエンスラボ (official website homepage)chromoscience.jp
2. 2会社概要 (official company profile page)chromoscience.jp
3. 3Chromosome Science Labo Inc. (Japan) - Wikidatawikidata.org