Bio-protocol
A peer-reviewed, open-access protocol journal and platform curating step-by-step life-science methods to improve research reproducibility.
Last updated September 28, 2026
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Overview
Bio-protocol is an open-access, peer-reviewed journal and online platform that publishes detailed, step-by-step experimental protocols across the life sciences. It was launched in 2011 by a group of Stanford postdoctoral researchers who wanted to address a persistent problem in scientific publishing: the methods sections of traditional research articles are often brief and incomplete, making experiments hard to reproduce without extensive troubleshooting. Bio-protocol's answer was to create a dedicated venue where protocols themselves are the primary content, curated and hosted for free access. The journal is published by Bio-protocol LLC, a company registered in California, USA, and is associated with Sunnyvale, California. Its editorial scope spans a broad range of life-science disciplines, including biochemistry, bioinformatics and computational biology, biophysics, cancer biology, cell biology, developmental biology, immunology, microbiology, molecular biology, neuroscience, plant science, stem cell biology, and systems biology. Protocols are organized into subject collections, and the journal publishes regular volumes and issues, with articles also available in press and in curated protocol collections. Bio-protocol positions itself around transparency and reproducibility. It argues that direct communication about methods among scientists improves the reliability of research, and it has expanded its scope beyond the journal itself to support that mission. The journal is listed in Web of Science and PubMed Central, giving its content visibility in major scholarly indexes. It operates on an open-access model with article processing charges, and it publishes under an open-access policy with defined content-availability and indexing practices. Authors can submit protocols by invitation, by self-submission, or on the recommendation of editors from collaborating journals. Submissions go through initial checks against the Bio-protocol manuscript template, followed by peer review and editorial handling. The journal's editorial leadership includes Editor-in-Chief Caroline Shamu, with Marisa Rosa as Managing Editor, supported by an editorial board and advisory board. Bio-protocol also maintains partnerships with other journals and professional memberships, and it invites researchers to become reviewers and to receive alerts about new protocols. In short, Bio-protocol is a specialized scientific publisher and platform brand rather than a general-interest media company. Its product is the curated protocol: practical, replicable methods content aimed at working life scientists, delivered through an open-access journal and website.
History
Bio-protocol was launched in 2011 by a group of Stanford postdoctoral researchers. The founding motivation was a practical one: the methods sections of conventional research articles are often brief and incomplete, so other scientists struggle to replicate experiments without extensive troubleshooting. The founders set out to create a dedicated, online, peer-reviewed protocol journal that would curate and host high-quality, free-access, step-by-step protocols across the life sciences. The journal is published by Bio-protocol LLC, a company registered in California, USA, and associated with Sunnyvale, California. From its base in the United States, it serves a worldwide community of life-science researchers. Over time, the journal developed a structured editorial operation with an Editor-in-Chief, a Managing Editor, an editorial board, and an advisory board, and it established formal submission pathways: protocols can be submitted by invitation, by self-submission, or on the recommendation of editors from collaborating journals. Bio-protocol built its content around subject areas spanning biochemistry, bioinformatics and computational biology, biophysics, cancer biology, cell biology, developmental biology, immunology, microbiology, molecular biology, neuroscience, plant science, stem cell biology, and systems biology. It publishes regular volumes and issues, maintains collections of protocols, and offers articles in press. The journal is listed in Web of Science and PubMed Central, and it operates under an open-access policy with article processing charges and defined content-availability and indexing practices. Beyond the journal, Bio-protocol has expanded its scope to support transparency and direct communication about methods among scientists, reflecting its core belief that better method-sharing improves research reproducibility. It maintains journal partnerships and professional memberships, and it engages its community by inviting researchers to become reviewers and to receive alerts about new protocols. Caroline Shamu serves as Editor-in-Chief, overseeing editorial policies and direction, with Marisa Rosa as Managing Editor.
- 2011
Bio-protocol is launched by a group of Stanford postdoctoral researchers.
Bio-protocol LLC is registered in California, USA, as the publisher of the journal.
The journal is listed in Web of Science and PubMed Central.
Caroline Shamu serves as Editor-in-Chief and Marisa Rosa as Managing Editor.
Products and positioning
Open-access, peer-reviewed protocol journal focused on improving research reproducibility through detailed, freely accessible methods.
Bio-protocol Journal
A peer-reviewed, open-access protocol journal listed in Web of Science and PubMed Central.
Protocol collections
Curated collections of step-by-step protocols organized by subject area.
Articles in press
Accepted articles made available ahead of final issue assignment.
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