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Bio Minerals

Belgian life-sciences company behind the patented ch-OSA® collagen-generator complex and the BioSil® supplement brand.

Last updated September 28, 2026

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Overview

Bio Minerals NV is a Belgian dietary-supplement company based in Destelbergen, near Ghent, and the maker of the BioSil® brand. Its business is built on a single patented molecule: choline-stabilized orthosilicic acid, marketed as ch-OSA®. Rather than selling animal-derived collagen peptides, Bio Minerals positions its products as "collagen generators" that activate the body's own production of collagen, elastin and keratin. The company states that it has invested in clinical research for over 30 years to support these natural mechanisms. The origin of the technology lies in academic work at the University of Antwerp, where a medical microbiologist identified choline as an ideal partner for stabilizing orthosilicic acid so that it remains biologically active in the human body. Bio Minerals NV was founded in 1994 to develop ch-OSA® for dietary supplements and to explore the complex's health benefits. The first consumer product, BioSil® vegan drops, reached health-food stores in the United States in 1995. A vegan capsule form followed in 2004, alongside expansion into Canada, and the brand entered Latin America in 2011. Bio Minerals has supported independent clinical research on its ingredient. A 2005 study by Barel et al. was described by the company as the first double-blind, placebo-controlled trial showing that a dietary supplement could improve skin, hair and nails; further work by Wickett et al. in 2007 and 2008 examined hair and bone endpoints. These studies underpin the brand's marketing claims, which cite figures such as 89% more skin elasticity, 30% fewer lines and wrinkles, and 26% stronger, smoother nails. Today the BioSil® range is sold largely through the brand's own e-commerce store, biosil.beauty, and through health-food and supplement retail channels. Products include Collagen Generator capsules, liquid capsules and drops; Advanced Hair Growth Formula; Advanced Hair & Nail Care; HerHarmony Beauty Blend; Healthy Aging; Advanced Bone Support; Skin Renew Elixir; GLP-1 Weightloss Recovery; and Daily Beauty Protein in vanilla and chocolate. The brand markets itself on clinical evidence, vegan and GMO-free formulations, and a "timeless, by design" positioning aimed at beauty-from-within and healthy-aging consumers.

History

Bio Minerals NV traces its origins to research at the University of Antwerp in the 1990s. A medical microbiologist there discovered that choline is the ideal partner for stabilizing orthosilicic acid, keeping it biologically active in the human body. This insight became the basis of the patented complex choline-stabilized orthosilicic acid, or ch-OSA®. Bio Minerals NV was founded in 1994 to develop ch-OSA® for use in dietary supplements and to explore the complex's potential health benefits. The first consumer product, BioSil® vegan drops, was launched in health-food stores across the United States in 1995, establishing the BioSil® brand as the company's consumer-facing identity. Expansion followed in the 2000s. In 2004 BioSil® introduced a second form, vegan capsules, and expanded into Canada. The company also invested in clinical research: in 2005 European university researchers Barel et al. published a study investigating BioSil®, which the company describes as the first-ever double-blind, placebo-controlled clinical study showing that a dietary supplement could improve skin, hair and nails. In 2007 a second team of independent researchers, Wickett et al., found that BioSil® supplementation significantly improves hair strength, thickness and elasticity; the company's timeline also lists a 2008 study by Wickett et al. on bones. International growth continued with a launch in Latin America in 2011. The company describes itself as having invested in clinical research for over 30 years to support the body's natural production and protection of collagen, elastin and keratin, and it emphasizes working with human physiology rather than introducing foreign products. In the 2020s Bio Minerals has broadened the BioSil® range beyond the original collagen-generator drops and capsules. Newer products include Advanced Hair Growth Formula, Advanced Hair & Nail Care, HerHarmony Beauty Blend, Healthy Aging, Advanced Bone Support, Skin Renew Elixir, GLP-1 Weightloss Recovery, and Daily Beauty Protein in vanilla and chocolate. The brand sells through its own biosil.beauty e-commerce store and health-food retail channels, and markets heavily on social platforms, with products flagged as trending on TikTok. Its messaging cites clinical results such as 89% more skin elasticity, 30% fewer lines and wrinkles, and 26% stronger and smoother nails.

  • 2011

    BioSil® launched in Latin America.

  • 2008

    Wickett et al. published research on BioSil® and bones.

  • 2007

    Wickett et al. found BioSil® supplementation significantly improves hair strength, thickness and elasticity.

  • 2005

    Barel et al. published the first double-blind, placebo-controlled study showing a dietary supplement could improve skin, hair and nails.

  • 2004

    BioSil® launched vegan capsules and expanded into Canada.

  • 1995

    First product, BioSil® vegan drops, launched in health food stores across the USA.

  • 1994

    Bio Minerals NV founded to develop choline-stabilized orthosilicic acid (ch-OSA®) for dietary supplements.

Products and positioning

Clinically proven, vegan collagen-generator supplements that activate the body's own collagen, elastin and keratin production rather than supplying animal-derived collagen.

  • Collagen Generator - Original Capsules

    Patented ch-OSA® complex in capsule form; activates the body's own collagen production rather than supplying animal-based peptides.

  • Collagen Generator - Liquid Capsules

    Patented ch-OSA® complex in a smooth, easy-to-swallow format.

  • Collagen Generator - Drops

    Flexible, absorbable drop format of the ch-OSA® complex.

  • Advanced Hair Growth Formula

    The brand's most powerful hair formula, clinically designed to reduce shedding, boost hair strength and grow over 12,000 extra growing hairs.

  • Advanced Hair + Nail Care

    Supercharges the patented ch-OSA® collagen generator to support hair and nails.

  • HerHarmony Beauty Blend

    2-in-1 formula combining clinically proven ch-OSA® with a 4g dose of Myo-Inositol and D-Chiro-Inositol (40:1) to support hormonal balance, hair, skin, nails and menstrual cycle.

  • Healthy Aging

    Blends patented ch-OSA® with Selenium to support skin and healthy aging.

  • Advanced Bone Support

    Combines patented ch-OSA® complex with Vitamin K2 and B12 to support bone health.

  • Skin Renew Elixir

    Liquid ch-OSA® collagen support with zinc, for smoother, firmer skin.

  • GLP-1 Weightloss Recovery

    Supports skin, hair and nails during GLP-1 weight-loss journeys.

  • Daily Beauty Protein (Vanilla / Chocolate)

    Combines patented ch-OSA® collagen generator with high-quality protein.

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