Bezwada Biomedical

Bezwada Biomedical is a United States-based specialty biomaterials company that develops and manufactures absorbable (bioabsorbable) polymers for biomedical applications. The company is headquartered at 15 Ilene Ct, Suite 1, Hillsborough Township, New Jersey, and operates ISO 13485 certified R&D and manufacturing facilities. Its self-described focus is narrow and deep: "We specialize in absorbable polymers for biomedical applications and that is all we do." Rather than offering a broad catalogue of commodity materials, Bezwada Biomedical positions itself as a polymer chemistry partner that helps device and pharmaceutical developers select or design the right absorbable polymer for a given application. The company's product portfolio spans PLGA (polylactic-co-glycolic acid) homopolymers and copolymers such as PLLA and PGA, blends of PLGA with polycaprolactone (PCL), polydioxanone (PDS) and polytrimethylene carbonate (PTMC), absorbable polyurethanes, polyoxaesters, functionalized amino acid polymers, functionalized natural products (including isoflavonoids), hydrolysable amines, PEG derivatives (acrylates and methacrylates), and nitric oxide- and drug-releasing polymers. These materials are supplied as research-grade and GMP-grade monomers and polymers, and are used as bioinks for 3D printing, adhesion prevention barriers, absorbable drug-eluting stent coatings, tissue adhesives and sealants, medical device coatings, drug delivery polymers, drug-device combinations, absorbable implantable devices and tissue engineering scaffolds. Bezwada Biomedical has received recognition from the U.S. National Science Foundation (NSF), including an NSF SBIR Phase II award for the development of a bioabsorbable tissue adhesive. The company also markets branded offerings such as ECO-BIOMAXX biobased polyurethanes, described as completely biodegradable and non-toxic, and TissuBond surgical sealant, described as absorbable, biocompatible and fast setting. Its founder, Rao S. Bezwada, is publicly associated with the company's absorbable polymer expertise and is listed as an inventor on polyoxaester patents. Because the company sells into regulated medical device and pharmaceutical supply chains, its value proposition centers on tunable physical, mechanical and degradation properties, fully hydrolysable chemistries, and the ability to add functional characteristics such as antimicrobial activity or controlled release of drugs like nitric oxide and aspirin directly into the polymer system. Bezwada Biomedical is a privately held company and does not appear to be listed on a public stock exchange.

Bezwada Biomedical is a privately held specialty biomaterials company based in Hillsborough Township, New Jersey, in the United States. Public information about the company is concentrated in its own technical and product communications and in a Wikidata entry that identifies it as a company in Somerset, United States. The company was founded by Rao S. Bezwada, whose name appears on polyoxaester patents listed by the company and who is publicly associated with its absorbable polymer expertise. From its inception, Bezwada Biomedical has concentrated on absorbable polymers for biomedical applications. Its stated philosophy is deliberately narrow: "We specialize in absorbable polymers for biomedical applications and that is all we do." This focus distinguishes it from larger diversified chemical and materials suppliers that offer absorbable polymers as one line among many. The company operates ISO 13485 certified R&D and manufacturing facilities and works at lab scale, pilot scale and analytical testing, which allows it to support customers from early feasibility through to GMP-grade supply. The company's technical platform began with PLGA (polylactic-co-glycolic acid) chemistry, described in its own materials as "the bread and butter of biodegradable medical device design." Bezwada Biomedical supplies PLGA homopolymers such as PLLA and PGA as well as copolymer blends, and then extends beyond PLGA by blending it with polycaprolactone (PCL), polydioxanone (PDS) and polytrimethylene carbonate (PTMC) to create a portfolio of degradable polymers with a wide range of physical, mechanical, biological and degradation properties. The company also developed polyoxaesters, a class of hydrophilic absorbable polyesters based on aliphatic diacids with oxygen atoms adjacent to their alpha-carbons, which are polymerized with a diol by polycondensation. According to the company, strategic placement of glycolic acid moieties in the polymer chains allows control of hydrophobic/hydrophilic properties and of degradation and absorption rates. Over time, Bezwada Biomedical expanded its platform into additional chemistries. It developed absorbable polyurethanes that are described as completely hydrolysable, biocompatible and tunable in physical and mechanical properties. It created functionalized amino acid polymers derived from natural amino acids, functionalized natural products including isoflavonoids that can be used as polymers or monomers, hydrolysable amines, and PEG derivatives such as acrylates and methacrylates. It also developed polymers that release nitric oxide and drugs simultaneously, and polymers with antimicrobial properties, extending the therapeutic value of device designs beyond simple mechanical scaffolding. The company has received recognition from the U.S. National Science Foundation. Its website states that it is an NSF SBIR Phase II Award Recipient and that it received an NSF award for bioabsorbable tissue adhesive development. It markets branded products including ECO-BIOMAXX biobased polyurethanes, described as completely biodegradable and non-toxic, and TissuBond surgical sealant, described as absorbable, biocompatible and fast setting. Its polymers are used as bioinks for 3D printing, adhesion prevention barriers, absorbable drug-eluting stent coatings, tissue adhesives and sealants, medical device coatings, drug delivery polymers, drug-device combinations, absorbable implantable devices and tissue engineering biomaterial scaffolds. Bezwada Biomedical remains a privately held company and does not appear to be listed on a public stock exchange. Its business model is built on supplying research-grade and GMP-grade monomers and polymers and on custom formulation work for medical device and pharmaceutical customers, rather than on high-volume commodity chemical sales.

• Bezwada Biomedical is founded by Rao S. Bezwada and establishes operations in New Jersey, United States.

• Company develops and commercializes a portfolio of PLGA homopolymers and copolymers, including PLLA and PGA.

• Bezwada Biomedical extends beyond PLGA with blends incorporating PCL, PDS and PTMC.

• Company develops polyoxaesters, a new class of hydrophilic absorbable polyesters.

• Bezwada Biomedical receives an NSF SBIR Phase II award for bioabsorbable tissue adhesive development.

• Company markets ECO-BIOMAXX biobased polyurethanes and TissuBond surgical sealant.

Specialist supplier of fully tunable, hydrolysable absorbable polymers for medical devices, drug delivery and regenerative medicine, offering research-grade and GMP-grade materials and custom formulation support.

• PLGA & Beyond PLGA

  PLGA homopolymers (PLLA, PGA) and copolymer blends, plus blends of PLGA with PCL, PDS and PTMC for a wide range of degradation and mechanical properties.

• Absorbable Polyurethanes

  Completely hydrolysable, biocompatible polyurethanes with tunable physical and mechanical properties.

• Polyoxaesters

  Hydrophilic absorbable polyesters based on oxadiacids and diols, with controllable hydrolysis and degradation profiles.

• Functionalized Amino Acid Polymers

  Synthetic absorbable polymers derived from natural amino acids with excellent engineering properties.

• Functionalized Natural Products

  Portfolio of functionalized isoflavonoids usable as polymers or monomers.

• Hydrolysable Amines

  Portfolio of hydrolysable amines for a variety of biomedical applications.

• PEG Derivatives (Acrylates and Methacrylates)

  Hydrolysable PEG and Pluronic based derivatives, including PEG acrylates and methacrylates for bioinks.

• Nitric Oxide & Drug Releasing Polymers

  Absorbable macromers or polymers that release nitric oxide and drug simultaneously.

• ECO-BIOMAXX Biobased Polyurethanes

  Completely biodegradable and non-toxic biobased polyurethanes.

• TissuBond Surgical Sealant

  Absorbable, biocompatible and fast-setting surgical sealant.

1. 1Bezwada Biomedical - Biomaterials Innovatorsbezwadabiomedical.com
2. 2Polymers - Bezwada Biomedicalbezwadabiomedical.com
3. 3Polyoxaesters - Bezwada Biomedicalbezwadabiomedical.com
4. 4PLGA & Beyond PLGA - Bezwada Biomedicalbezwadabiomedical.com
5. 5Bezwada Biomedical (United States) - Wikidatawikidata.org