B.E.MARUBISHI Co., Ltd.
Japanese specialist manufacturer of culture apparatus and bioprocess equipment, engineering bridges from biotechnology to the bioindustry since 1954.
Last updated September 28, 2026
AI crawler reads
No AI crawler has read this profile since Oct 28, 2026.
Overview
B.E.MARUBISHI Co., Ltd. (丸菱バイオエンジ) is a Japanese engineering and equipment company specializing in culture apparatus (fermenters) and bioprocess machinery. Founded in August 1954 as a division of Marubishi Kogyo Co., Ltd., the business began manufacturing and selling small-scale fermentation equipment at a time when the word "biotechnology" had not yet been coined. It was separated in 1957 as Marubishi Seisakusho, reorganized in 1959 as Marubishi Rika Sochi Kenkyusho Co., Ltd. with capital of 1,000 thousand yen, and in 1984 changed its name to Marubishi Bioengineering Co., Ltd. The company is headquartered in Chiyoda City, Tokyo, and operates a Chiba factory in Chiba City, plus sales offices in western Japan and a Thai subsidiary, B.E.Marubishi (Thailand) Co., Ltd. The company designs and manufactures culture apparatus for general microorganisms, animal and plant cells, and special-condition equipment such as pressurized culture systems. Its bioprocess units include single-use units, continuous centrifugal separation units, and membrane separation and concentration units. It also provides validation support and full engineering services covering basic planning, construction, maintenance, and decommissioning of bioprocess facilities. Its products serve upstream and downstream bioprocesses across biopharmaceuticals, regenerative medicine, environmental energy, fine chemicals, and food and brewing. B.E.MARUBISHI positions itself as a "total supporter" of bio-related equipment, offering capacities from under 1 liter to over 15 kL for microbial culture. It has pursued advanced initiatives such as practical bioreactors for high-efficiency biomass energy production and automated culture systems for mesenchymal stem cells. The company received the Science and Technology Agency Director-General's Award in 1989 and ISO 9001:2000 certification in 2005. It remains a privately held Japanese company, with Toshihiko Yamagata serving as Representative Director and President.
History
B.E.MARUBISHI Co., Ltd. traces its origins to August 1954, when Marubishi Kogyo Co., Ltd. was established and one of its divisions began manufacturing and selling small-scale fermentation apparatus. At that time the term "biotechnology" did not yet exist, and the company describes itself as having been born alongside the dawn of the field. In August 1957, the small fermentation apparatus division was separated and established as Marubishi Seisakusho in Konya-cho, Chiyoda Ward, Tokyo. In March 1959, the organization was changed to Marubishi Rika Sochi Kenkyusho Co., Ltd. (Marubishi Physical and Chemical Apparatus Research Institute), starting as a specialized manufacturer of fermenters with capital of 1,000 thousand yen. In March 1961, the company built the Okudo Factory in Katsushika Ward, Tokyo, and in April 1961 began overseas exports. In March 1967, the head office was relocated to Kajicho, Chiyoda Ward, Tokyo. In July 1972, the Chiba Factory was built at 55-6 Chigusa-cho, Hanamigawa Ward, Chiba City. In August 1981, as overseas transactions expanded, the export division was spun off as Marubishi Trading Co., Ltd. In March 1984, the company changed its name to Marubishi Bioengineering Co., Ltd. (株式会社丸菱バイオエンジ). In April 1989, the company received the Science and Technology Agency Director-General's Award. In November 1989, the head office moved to 2-10-15 Higashikanda, Chiyoda Ward, Tokyo. In April 1991, Tamiyoshi Yamagata (former chairman, deceased) received the Medal with Yellow Ribbon, and in May 2001 he was awarded the Order of the Sacred Treasure, Gold Rays with Rosette. In February 2004, Marubishi Thailand Co., Ltd. was established in Bangkok, Thailand. In February 2005, the company obtained ISO 9001:2000 certification for its head office and factory. In September 2007, Tamiyoshi Yamagata received the first Biotechnology Distinguished Service Award from the Society for Biotechnology, Japan. In September 2008, Marubishi Thailand Co., Ltd. built its factory and training center. In April 2014, the head office moved to 2-10-14 Higashikanda, Chiyoda Ward, Tokyo. In April 2016, the Osaka Sales Office moved to FS Building 201, 4-2-6 Nunobikicho, Chuo Ward, Kobe City, Hyogo Prefecture. Over more than six decades, the company has grown with the development of biotechnology, providing bioprocess equipment and engineering to serve as a bridge to the bioindustry. Its product history includes two-tank, three-type fermentation apparatus in 1954, twelve MSJ-U30L automatic culture apparatus in 1970, pilot plants in 1980, and culture, cell separation, and concentration equipment with validation for the biopharmaceutical field in 2000. The company continues to pursue advanced initiatives such as practical bioreactors for high-efficiency biomass energy production and automated culture systems for mesenchymal stem cells.
Marubishi Kogyo Co., Ltd. established; one division begins manufacturing and selling small fermentation apparatus.
Small fermentation apparatus division separated and established as Marubishi Seisakusho in Konya-cho, Chiyoda Ward, Tokyo.
Reorganized as Marubishi Rika Sochi Kenkyusho Co., Ltd., starting as a specialized fermenter manufacturer with capital of 1,000 thousand yen.
Okudo Factory built in Katsushika Ward, Tokyo.
Overseas exports began.
Head office relocated to Kajicho, Chiyoda Ward, Tokyo.
Chiba Factory built at 55-6 Chigusa-cho, Hanamigawa Ward, Chiba City.
Export division spun off as Marubishi Trading Co., Ltd. due to expanding overseas transactions.
Company name changed to Marubishi Bioengineering Co., Ltd.
Received the Science and Technology Agency Director-General's Award.
Products and positioning
A total supporter of bio-related equipment, bridging biotechnology to the bioindustry through culture apparatus and bioprocess engineering.
Culture apparatus
Designed and manufactured for general microorganisms, animal and plant cells, and special conditions such as pressurized culture.
Bioprocess units
Includes single-use units, continuous centrifugal separation units, and membrane separation and concentration units.
Validation support
Validation services backed by long experience in culture plant manufacturing.
Engineering
Proposals covering all phases of bioprocess construction from basic planning to maintenance and removal.
Sources5 sources
Cite this profile: Cite the canonical profile. /brand-wiki/bemarubishi-co-ltd-japan · Editorial policy · How profiles are compiled