Avantyx

Avantyx LLC is a privately held medical company headquartered in Miami, Florida, in the United States. According to its official website, the company is focused on developing preventative treatments for chemotherapy-induced and diabetic peripheral neuropathy, a condition in which damage to peripheral nerves causes severe pain, numbness, tingling and temperature sensitivity. The company describes its mission as addressing the root cause of nerve damage rather than only managing symptoms, with the goal of preventing nerve damage and restoring nerve function. Avantyx frames its work around a large and underserved patient population. It cites that roughly 60% of diabetic patients develop peripheral neuropathy and that about 50% of chemotherapy patients suffer from irreversible nerve damage, while around 30% of chemotherapy patients experience dose alteration or interruption of treatment because of severe neuropathy. It also states that 500 million people worldwide and 30 million Americans suffer from peripheral neuropathy without effective treatment options on the market today. The company notes that peripheral neuropathy is predominantly caused by diabetes, chemotherapy, alcoholism, HIV, as well as genetic and auto-immune disorders. The company says its research team, after studying the root cause of peripheral neuropathy for many years, made a breakthrough discovery by identifying a unique mechanism that causes peripheral nerve damage. Avantyx states that it is currently working on a therapeutic intended to prevent and restore nerve damage caused by diabetes and chemotherapy. By targeting the root cause of nerve damage, the company says its innovative therapeutic drug will not only prevent nerve damage but restore nerve function. Its stated goal is to enable chemotherapy patients to complete their treatment without the detrimental side effects that currently result in dose alteration and interruption of life-saving treatment. Avantyx is led by Sandra Rieger, Ph.D., described on its website as an internationally recognized scientist who has been working on sensory neuropathy, and Bianca Ruiz. Dr. Rieger is listed as Founder & CEO and Bianca Ruiz as Founder & COO. The company operates as a private medical company and, as of the available evidence, is not publicly listed. Its public-facing presence centers on its official website, which presents its mission, research problem, research solution, team, and press and educational links.

Avantyx LLC is a medical company based in Miami, Florida, in the United States. Public information about the company is limited and is drawn primarily from its official website and a Wikidata entry describing it as a medical company in Miami. The company's website presents its mission, the research problem it addresses, its proposed research solution, its team, and links to press and educational material. According to its website, Avantyx was founded around a mission to develop preventative treatments for chemotherapy and diabetic peripheral neuropathy, with a deep understanding of the root cause of nerve damage. The company states that its research team studied the root cause of peripheral neuropathy for many years and made a breakthrough discovery by identifying a unique mechanism that causes peripheral nerve damage. Building on that discovery, Avantyx says it is currently working on a therapeutic that will prevent and restore nerve damage caused by diabetes and chemotherapy. The company's leadership includes Sandra Rieger, Ph.D., listed as Founder & CEO, and Bianca Ruiz, listed as Founder & COO. Dr. Rieger is described on the website as an internationally recognized scientist who has been working on sensory neuropathy. The website does not provide a founding date, funding history, or details of clinical development stages in the available evidence. Avantyx frames its work against a substantial unmet medical need. It cites that 60% of diabetic patients develop peripheral neuropathy and that 50% of chemotherapy patients suffer from irreversible nerve damage, while 30% of chemotherapy patients experience dose alteration and interruption of treatment due to severe neuropathy. It also states that 500 million people worldwide and 30 million Americans suffer from peripheral neuropathy without any effective treatment options on the market today. The company notes that peripheral neuropathy is predominantly caused by diabetes, chemotherapy, alcoholism, HIV, as well as genetic and auto-immune disorders, and that patients suffer from severe pain, numbness, tingling and temperature sensitivity. The company's stated goal is to enable chemotherapy patients to complete their treatment without the detrimental side effects that currently result in dose alteration and interruption of life-saving treatment. By targeting the root cause of nerve damage, Avantyx says its innovative therapeutic drug will not only prevent nerve damage but restore nerve function, with the aim of transforming lives, reducing mortality rates, and increasing positive treatment outcomes. As of the available evidence, Avantyx operates as a private medical company and is not publicly listed.

• Avantyx LLC is described as a medical company in Miami, United States.

  [2]Avantyx LLC - Wikidatawikidata.org
• Company website states its research team identified a unique mechanism causing peripheral nerve damage after years of studying the root cause of peripheral neuropathy.

  [1]Nerve Regeneration | Avantyx LLCavantyxpharma.com
• Company states it is currently working on a therapeutic to prevent and restore nerve damage caused by diabetes and chemotherapy.

  [1]Nerve Regeneration | Avantyx LLCavantyxpharma.com

A research-stage medical company developing disease-modifying therapeutics for peripheral neuropathy, positioning itself around root-cause science and prevention/restoration of nerve damage.

• Investigational therapeutic for chemotherapy- and diabetic peripheral neuropathy

  A therapeutic in development intended to prevent and restore nerve damage caused by diabetes and chemotherapy by targeting the root cause of nerve damage.

1. 1Nerve Regeneration | Avantyx LLCavantyxpharma.com
2. 2Avantyx LLC - Wikidatawikidata.org