Aptose Biosciences (United States)

Aptose Biosciences is a science-driven clinical-stage biotechnology company committed to precision medicines addressing unmet clinical needs in oncology, with an initial focus on hematology. Its small molecule cancer therapeutics pipeline includes products designed to provide single agent efficacy and to enhance the efficacy of other anti-cancer therapies and regimens without overlapping toxicities. The company has two clinical-stage investigational products for hematologic malignancies: tuspetinib, an oral, potent myeloid kinase inhibitor, and luxeptinib, an oral, dual lymphoid and myeloid kinase inhibitor.

Aptose Biosciences is a science-driven clinical-stage biotechnology company committed to precision medicines addressing the unmet clinical needs in oncology, with an initial focus on hematology. The company's small molecule cancer therapeutics pipeline includes products designed to provide single agent efficacy and to enhance the efficacy of other anti-cancer therapies and regimens without overlapping toxicities. Aptose Biosciences has two clinical-stage investigational products for hematologic malignancies: tuspetinib, an oral, potent myeloid kinase inhibitor, and luxeptinib, an oral, dual lymphoid and myeloid kinase inhibitor. The company is based in San Diego, United States.

Precision Oncology for Therapies of Tomorrow

• Tuspetinib (formerly HM43239)

  A potent oral inhibitor of key kinases operative in myeloid malignancies, including SYK, FLT3, JAK, c-KIT(mut), and others.

• Luxeptinib

  A potent non-covalent inhibitor of wildtype and mutant forms of BTK, as well as multiple oncogenic signaling pathways operative in CLL and other B-cell malignancies; also potently inhibits wildtype and all mutant forms of FLT3 which are oncogenic drivers in AML and MDS, as well as other oncogenic rescue pathways operative in myeloid malignancies.

1. 1Aptose Biosciences Inc. (APS)aptose.com
2. 2About :: Aptose Biosciences Inc. (APS)aptose.com
3. 3Management Team :: Aptose Biosciences Inc. (APS)aptose.com
4. 4Board of Directors :: Aptose Biosciences Inc. (APS)aptose.com