American Journal of Therapeutics
American Journal of Therapeutics is a bimonthly medical journal focused on drug therapy, comparative effectiveness, and post-marketing surveillance.
Last updated August 25, 2026
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Overview
American Journal of Therapeutics is a peer-reviewed medical journal covering developments in therapeutic medicine. Established in 1994 by John Somberg, MD, the journal publishes research and clinical analysis concerning drug therapy, comparative effectiveness research, and post-marketing surveillance. Its subject area places it at the intersection of pharmacology, clinical medicine, therapeutics, and evidence-based healthcare decision-making. The journal is published on a bimonthly schedule by Wolters Kluwer through its Lippincott Williams & Wilkins publishing operations. Its intended readership includes physicians, clinical researchers, pharmacologists, healthcare professionals, and others who evaluate the benefits, risks, and real-world performance of medical treatments. As a specialist periodical, its content supports both the interpretation of emerging therapeutic evidence and the assessment of established treatments after they enter routine clinical use. The journal has been included in the Index Medicus and MEDLINE, increasing the discoverability of its articles within the biomedical literature. It has also been part of the Web of Science Core Collection since 2010. Journal Citation Reports reported a 2022 impact factor of 4.2; this figure is a journal-level bibliometric measure for that reporting year rather than a direct measure of the quality of any individual article. Peter Manu, MD, has served as editor-in-chief since 2015. He is identified as a professor of medicine at the Zucker School of Medicine at Hofstra/Northwell. The journal's identity is principally editorial and scholarly rather than consumer-facing: its core offering is a continuing publication that disseminates clinically relevant therapeutic evidence through print and digital journal channels.
History
American Journal of Therapeutics was established in 1994 by John Somberg, MD, as a medical journal dedicated to therapeutic practice and evidence concerning the use of medicines. From its beginning, the journal's scope has centered on drug therapy and clinically relevant evaluation of treatments rather than on a single disease area or one narrow pharmaceutical discipline. Its coverage includes comparative effectiveness research, which examines how alternative interventions perform relative to one another, and post-marketing surveillance, which assesses treatment safety and effectiveness after products have entered broader clinical use. The publication operates as a specialist scholarly journal for the medical and research communities. Its articles are intended to help clinicians and investigators interpret therapeutic evidence, compare treatment approaches, and understand information that develops through routine use of medicines. This places the journal within the broader evidence-based medicine ecosystem, where published clinical findings, treatment comparisons, and post-market observations contribute to decisions about patient care and health policy. Wolters Kluwer publishes the journal through its Lippincott Williams & Wilkins operations. The title is issued bimonthly and is available through the publisher's journal platform, giving it both a continuing periodical presence and a digital distribution channel. The publisher's role connects the journal to an established medical and scientific publishing portfolio, while the journal itself retains a distinct editorial identity under its title. A significant stage in the journal's scholarly development came in 2010, when it became part of the Web of Science Core Collection. The title is also included in Index Medicus and MEDLINE, two important discovery and indexing systems for biomedical literature. These listings improve the ability of researchers and health professionals to locate its articles and support the journal's participation in formal scholarly citation networks. Peter Manu, MD, has been editor-in-chief since 2015. He is identified as a professor of medicine at the Zucker School of Medicine at Hofstra/Northwell. Under an editorial structure led by a physician academic, the journal continues to present itself as a clinically oriented publication concerned with the evaluation and application of therapeutics. Journal Citation Reports reported a 2022 impact factor of 4.2. This bibliometric result provides one indicator of citation activity for the journal during the relevant reporting period, but it does not represent a financial result or a quality judgment about individual contributions. Publicly available reference material provides limited information about the journal's detailed editorial board, submission volume, circulation, revenue, or ownership arrangements beyond its publication by Wolters Kluwer. The available record therefore supports describing American Journal of Therapeutics as an active, internationally accessible medical journal with a long-running focus on drug therapy and therapeutic evidence.
- 2022
Reported impact factor
[1]Journal Citation Reports listed a 2022 impact factor of 4.2.
- 2015
Peter Manu appointed editor-in-chief
[1]Peter Manu, MD, began his tenure as editor-in-chief.
- 2010
Added to the Web of Science Core Collection
[1]The journal became part of the Web of Science Core Collection.
- 1994
Journal established
[1]John Somberg, MD, established American Journal of Therapeutics as a medical journal covering therapeutic medicine and drug treatment.
Products and positioning
A specialist clinical medicine journal focused on practical therapeutic evidence, medication use, comparative treatment effectiveness, and safety or performance information emerging after market introduction.
Medical and scientific journal · 1994
American Journal of Therapeutics
The journal's principal offering is a bimonthly, peer-reviewed publication addressing drug therapy, comparative effectiveness research, and post-marketing surveillance. It serves clinicians, medical researchers, pharmacologists, and other healthcare professionals seeking evidence about the practical use, relative performance, and ongoing safety of therapeutic interventions. The title is distributed through Wolters Kluwer's Lippincott Williams & Wilkins journal platform and is indexed in major biomedical and scholarly information systems.
Recent events
- 2022
Journal Citation Reports lists a 2022 impact factor of 4.2[1]
Other
Journal Citation Reports reported an impact factor of 4.2 for the 2022 reporting year.
- 2015
Peter Manu becomes editor-in-chief[1]
Leadership change
Peter Manu, MD, began serving as editor-in-chief of the journal.
- 2010
American Journal of Therapeutics enters the Web of Science Core Collection[1]
Other
The journal became part of the Web of Science Core Collection, expanding its visibility in major scholarly citation and indexing infrastructure.
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