Adagene Inc.

Adagene is a Nasdaq-listed, global, clinical-stage immunotherapy company that redefines the discovery and design of antibodies to open new horizons in the treatment of cancer. Its platform combines computational biology and artificial intelligence to create novel antibodies intended to overcome safety issues and improve efficacy. The company describes a Dynamic, Multi-Purpose Discovery Engine and a Dynamic Precision Library driving a pipeline of programs with potential to be first or best in class, alongside disclosed global partnerships and collaborations.

Adagene is a Nasdaq-listed, global, clinical-stage immunotherapy company redefining the discovery and design of antibodies to open new horizons in the treatment of cancer. Its core technology is built upon an understanding of the role that protein folding and the motion of molecules play in giving rise to dynamic conformational diversity, where an amino acid sequence can adopt multiple structures and functions. Adagene has created a platform composed of unique, multi-purpose antibody technologies and a growing pipeline of leading assets with novel mechanisms of action. Driven by a platform combining computational biology and artificial intelligence, the company creates novel antibodies intended to overcome safety issues and improve efficacy. Its discovery engine, the Dynamic Precision Library, drives a pipeline of programs with potential to be first or best in class, and the company has forged strategic partnerships with multiple global companies.

Redefining the discovery and design of therapeutic antibodies; platform-driven precision immunotherapy by multiple modalities.

• ADG106

  CD137/4-1BB agonist with unique epitope and novel MOA

• ADG116

  Novel CTLA-4 antagonist with unique epitope for effective Treg depletion and soft CTLA-4 ligand blocking

• ADG126

  Lead SAFEbody program targeting CTLA-4, designed to enhance the safety profile of a CTLA-4 targeting antibody

• NEObody

  Targeting unique epitope with novel MOA

• SAFEbody

  Precision masking and local activation in TME

• POWERbody

  Empowered efficacy with local activation in TME

1. 1Home - Adageneadagene.com
2. 2Company Overview - Adageneadagene.com
3. 3Collaborations - Adageneadagene.com
4. 4Leadership Team - Adageneadagene.com