Plot
In Los Angeles, the city and neighborhoods are constructed from corporate emblems: Bentley and Aston Martin logos soar overhead like birds in flight, while MSN's butterflies flutter nearby; the AOL Man appears as pedestrians strolling along the streets; and highway signs display logos from Atlantic Records among others. The original Pringles mascot drives through Malibu, eventually parking in a diner's lot and approaching a break-time Esso waitress smoking a Air France cigarette, trying to flirt, but she declines, tossing her cigarette aside as she walks off.
Meanwhile, by from the Santa Monica Pier, two police officers as Michelin Men named Mitch and Mike are parked in the police cruiser discussing zoo animal captivity. Their conversation ends when Mike is sent to pick up lunch from KFC for both. As he leaves with a soft drink bearing a Dunkin' Donuts logo and a bucket of fried chicken, a criminal called Ronald McDonald is seen smuggling weapons in a red delivery van at a nearby gas station selling diesel. Mitch receives a message on the radio, revealing that the criminal is now on the loose.
Spotting Ronald in shock from afar, Mike rushes outside KFC, accidentally bumping into Fido Dido and knocking him over. Once in the car, the police pursue Ronald; during the chase, innocent bystanders and motorists suffer accidental injuries and crash their vehicles. Across town, BiC Boy students, along with Big Boy and Haribo Boy, are on a guided tour of the Los Angeles Zoo led by a flamboyant Mr. Clean; tired of the tour, Big Boy and Haribo Boy leave the train and run to the lion exhibit. There, they disturb the MGM lion while he sleeps: Haribo moons him, and Big Boy throws an empty Coke bottle at him while insulting him, prompting the zoo's owner, the Jolly Green Giant, to reprimand them.
Meanwhile, the chase starts on the highway, endangering more motorists, pedestrians, and drivers as Ronald and the police speed along an off-ramp leading in a Street in town. The tour group quickly boards their school bus, leaving the zoo en route to the Pizza Hut where the chase is broadcast live on a television set, while Esso Girl serves coffee to the original Pringles mascot and the Hot & Spicy mascot, assisted by the Pillsbury Doughboy. When Esso Girl approaches, she is groped by the Hot & Spicy mascot, causing her to drop the mug which shatters on the tile, leaving an coffee spill. The chase starts again. risking a lot of motorists, pedestrians, and drivers as Ronald and the police race along an off-ramp, where Red and Yellow are hit and killed at the crosswalk by the cruiser (a piece of M&M candy belonging to Yellow hits the windshield but slides off), despite narrowly avoiding the van. The pursuit ends when Ronald brakes and swerves to avoid the school bus but crashes into a car and a semi-truck, causing his van to slide onto the sidewalk and grass, stopping in front of the Pizza Hut, striking its sign, and crashing the pole, shocking the customers and the Esso Girl inside.
Several guns and biological weapons spill from the wrecked van onto the sidewalk and curb as police arrive. The officers prepare to arrest Ronald and secure the scene, while Big Boy and Haribo Boy, who have exited the school bus, sneak away from the teacher to steal some of the van's disturbed contents for black market sale. Ronald exits his wrecked vehicle, frightening the children, then kicks Haribo Boy unconscious and uses a Heckler & Koch MP5 to take Big Boy hostage. He runs into the Pizza Hut with Big Boy, but Big Boy bites his arm to escape and crawls to the counter where Esso Girl is hiding, as Ronald attempts to shoot him. Police are authorized to open fire, but Ronald retaliates by kicking the glass wall to shoot at them (even denting police cars and shooting a neon sign at a Hard Rock Cafe), after Mitch disobeys orders to hold fire—accidentally hitting Mr. Peanut in the head with a sniper bullet, shattering his shell and causing the nut inside him to fall onto the floor.
The sheriff then calls in SWAT reinforcements, which are delivered to a nearby rooftop to snipe Ronald's head.
As gunfire erupts, a distant tremor shakes Los Angeles, causing a Michelin Man to miss Ronald's head—his intended sniper target—which results in the bullet hitting the diner's roof, ricocheting off the sign's dome, and striking a helicopter's tail rotor, causing it to lose altitude and crash into a Pizza Hut. Thankfully, no one is injured except the Airplane pilot, who loses consciousness, triggering an earthquake. The animals escape, with an elephant running into the Jolly Green Giant and carrying him off after he tries to stop them.
Big Boy and Esso Girl manage to escape the collapsing Pizza Hut with the Pillsbury Doughboy, while the original Pringles mascot and the Hot & Spicy mascot are crushed inside after hiding under a booth. The two hijack Mitch and Mike's police cruiser to flee the scene as the earthquake creates a fissure in the street resembling the Microsoft Gaming Xbox logo that engulfs it. Meanwhile, Mitch attempts to shoot Ronald, but he shoots Mitch in the forehead after he approaches him. Ronald then sneaks away, noticing a row of Grease 2 motorcycles, and rides off on one of them, doing a donut maneuver first as he departs.
While on the move, as zoo animals rampage through the city, he dodges wrecked vehicles, debris, and falling signs, including those for Enron, Freddie Mac, and Kmart, using a fallen Nabisco sign as a ramp. Just as he is about to escape, he crashes into a fallen Weight Watchers sign blocking his way, flying onto the road and sliding into a crevasse resembling the Zenith Electronics logo. When attempting to climb out, he is run over by Esso Girl and Big Boy, but they narrowly escape the city and head toward the hills via Route 66, traveling along a curved highway shaped like the Vaio logo.
The earthquake still continues spreading through the desert and into Marlboro Country, where it forms a canyon amongst an oil field. Approaching the Hollywood Chewing Gum Sign, it disintegrates and slides down the hill onto the highway. While avoiding one of the fallen letters, the duo veers off the highway, crashes through a guardrail, and tumbles down a hill, ending in a collision with an apple tree resembling the American Century Investments logo that nearly kills them (they did not have time to put on seat belts) and causes one of the cruiser's front wheels to come off and roll away, scattering its apples violently (some roll away) and stopping the earthquake.
Petroleum erupts from the newly formed desert canyon, flooding Los Angeles and sweeping everything away, prompting some to climb onto the highest points of remaining structures, which serve as islands amid the flooded city and floating debris that stay afloat, all while avoiding hungry crocodiles and trying to find help.
The hill supporting the cruiser, with Esso Girl and Big Boy inside, splits open, revealing a massive The North Face logo, as the surrounding land disintegrates. The remaining land sinks into the sea, leaving behind a tiny island where the duo is stranded. Esso Girl picks up a nearby colored apple and bites into it while lying next to Big Boy on the newly formed island, now part of Southern California and the Baja California peninsula, separated from the mainland and shaped like Nike's swoosh logo, with the Earth depicted as the Universal Pictures logo, featuring the Moon and the Sun.
Finally, it is revealed that outer space, including the planets, are composed of countless logos: Mars representing Red Planet, Orion Pictures as a constellation, the Milky Way Galaxy with its stars, and Pioneer replacing Pioneer 11, etc. Additionally, it is shown that Ronald survived being run over, suffering only severe baldness, a black eye, unfocused eyes, and some missing teeth.
