Nicotine withdrawal is a group of symptoms that occur in the first few weeks after stopping or decreasing use of nicotine. Symptoms include intense cravings for nicotine, anger or irritability, anxiety, depression, impatience, trouble sleeping, restlessness, hunger, weight gain, and difficulty concentrating.[1][2][3] Withdrawal symptoms make it harder to quit nicotine products, and many smoking cessation methods aim to reduce these symptoms.[1] Smoking cessation programs can help increase the chances of success.[1] Nicotine withdrawal is recognized in both the American Psychiatric Association Diagnostic and Statistical Manual (DSM) and the WHO International Classification of Diseases (ICD).