Operational career
MSC Virtuosa was scheduled to begin sailing weekly itineraries in the Western Mediterranean in autumn 2020.[5] However, due to the construction delays, MSC Grandiosa replaced all of the ship's scheduled itineraries through the winter 2020–2021 season.[17] She entered service on 20 May 2021 with a series of three and four-night cruises from Southampton, before beginning seven-night cruises around the British Isles on 12 June with three embarkation ports in England and Scotland.[16] These cruises sailed to ports such as Portland, Liverpool, Greenock and Belfast and are exclusively for UK residents.[18] She was originally scheduled to cruise in Northern Europe and the Baltic region for the spring 2021 season, however these cruises were operated by MSC Seaview instead.[19] She re-positioned to Dubai in autumn 2021, where she was based throughout the winter, sailing 7-day itineraries in the Persian Gulf to the UAE, Qatar, Saudi Arabia and Oman.[20]
In 2022, MSC Virtuosa returned back to Southampton for a summer season from May until November 2022.[21] Whilst in Southampton she will perform 2–14 night cruises to regions including Northern Europe, Baltics, Norwegian Fjords and the Canary Islands.
Southampton is her main embarkation port during the season, with additional embarkation ports of Malaga, Spain and Lisbon, Portugal. In August 2022, it was announced MSC Virtuosa will be based in Southampton year-round and into summer 2023.[22]
On 27 October 2025, MSC Virtuosa entered dry dock for the first time since her launch at Damen Verolme Rotterdam, carrying out routine maintenance, without a focus on cosmetic upgrades. She will depart the dry dock on 19 November 2025 at 17:00 CEST, commencing a 17-night transatlantic repositioning cruise to the Caribbean.[23]