On 19 March 1964, The Rolling Stones performed at the venue.[30] On 10 March 1970, The Faces performed there. On 30 April 1972, the theatre was the venue for The Goon Show's reunion episode, The Last Goon Show of All; several senior members of the royal family attended this episode, which was filmed and recorded.
On 2 March 1978, The Jam performed, with the concert recorded and released as part of the 2015 box set Fire and Skill – The Jam Live, then subsequently given a limited standalone vinyl release.
On 24-26 July 1978, The Clash performed, with the concerts recorded and released as part of the 1978 movie Rude Boy (film).
On 10 September 1979, heavy metal band Iron Maiden performed a gig at The Music Machine. The band, at the time, consisted of Steve Harris (bass), Dave Murray (lead guitar), Paul Di'Anno (vocals), Tony Parsons (lead guitar) and Doug Sampson (drums).
On 14 November 1980, The Music Machine hosted an infamous gig by London mod revival band the Chords, where onstage interactions between the band members ranged from frosty to outright hostile and following the gig, the Chords' frontman Billy Hassett left the band acrimoniously and was later replaced by Kip Herring.
In 1985, Steve Marriott performed with his band Packet Of Three.
The cult London electronic band You You You, consisting of Karen O'Connor, Laurence Malice, and Iain Williams,[31] performed their debut concert at the Camden Palace on January 13, 1987.[32] The band billed their first series of concerts as 'Stage 1' of their 'World Domination Tour'[33] and enlisted the help of illustrator Mark Wardel to design their publicity. Their appearance at the Camden Palace attracted over 1,000 people on what the Met Office recorded as probably being England's coldest night of the 20th Century.[34]
In 2005, a year after restoration, Coldplay chose Koko to launch their album X&Y.[35] Later that year, Madonna also hosted her album launch of Confessions on a Dance Floor at Koko.[17]
The next year, in 2006, Elton John hosted a benefit party at Koko for his AIDS Charity Bash, attended by Natalie Imbruglia, Elle Macpherson, Jade Jagger, and Kevin Spacey.[8][36]
Prince performed a secret show at Koko in 2007. [37] The American band My Chemical Romance also played a private show at Koko in 2007, hosted by BBC Radio 1.[14] Later in 2007, The Disney Channel used Koko to host Hannah Montana's Live in London, an exclusive one-off event broadcast globally for her fans.[14][38][39]
In 2008, Siouxsie Sioux recorded a live DVD at Koko called Finale: The Last Mantaray & More Show, which was released the following year.
In 2009, Koko hosted the iTunes festival, which extended over 30 nights and featured guests including N.E.R.D, Paul Weller, James Blunt, Calvin Harris and Dizzee Rascal and over 45,000 people.[40]
In 2010, Koko also hosted fundraiser for the Institute of Contemporary Arts, featuring a performance Lily Allen and Bryan Ferry and attended by Vivienne Westwood, Damien Hirst, and Tracey Emin.[41]
Since its restoration, the club has attracted well known musicians and DJs including: The Damned, Terrorvision, Al Murray, Irfan Latif, Don Broco, Red Hot Chili Peppers, Madonna, Christina Aguilera, Coldplay, Tori Kelly, Katy B, My Chemical Romance, Emma Marrone, Oasis, Bruno Mars, Thom Yorke, Amy Winehouse, La Roux, James Marriott, Skrillex, Lady Gaga, The Killers, Kanye West, Katy Perry, Tokio Hotel, Lily Allen, Poppy, Demi Lovato, Usher, Noel Gallagher, Wargasm, Swedish House Mafia, JoJo, Azealia Banks, VNV Nation, Rolling Blackouts Coastal Fever, Masters at Work and many others.[12][17][42]
In 2017 Ed Sheeran performed a private concert to promote his third studio album ÷ in partnership with UK radio station Capital FM, as also Ariana Grande in September 2018 to promote her fourth studio album, Sweetener.