Centrum is an American brand of multivitamins produced by Haleon. It was designed by Dr. Ellenbogen's team, working at Lederle Laboratories, and was introduced in 1978. It has been owned by Wyeth, Pfizer, GSK,[1] and now Haleon.
Physicians' Health Study II
In 2012, the Physicians' Health Study II (PHS-II) found that participants who took a Centrum-brand multivitamin each day for an average of 11 years had no change in cancer mortality or cardiovascular disease mortality compared to the placebo group. The authors did find a slight reduction in cancer incidence although this conclusion was questioned in the Journal of the American Medical Association.
On October 17, 2012, researchers reported on a double-blind study of 14,641 male U.S. physicians initially aged 50 years or older (mean age of 64.3, standard deviation 9.2 years), that began in 1997 with treatment and follow-up through June 1, 2011.