Carbolabs, Inc., is an American chemistry company specializing in reactions utilizing phosgene, founded by Joe Karabinos in 1967. Originally located in the basement of his home in Bethany, Connecticut,[1] it was not until the following year that the business was moved into its own dedicated building. The company was purchased by Sigma Aldrich in 1998.[2] In 2008 operations at the Bethany site were discontinued and were subsequently moved to the Sheboygan Falls, Wisconsin Sigma Aldrich manufacturing facility. Carbolabs uses phosgene to produce a wide array of chemicals including isocyanates, chloroformates, and isonitriles,[3] although some reactions not involving phosgene such as the production of the fluorinating reagent DAST[4] are also part of their established chemistries. As a subsidiary of Sigma Aldrich, a number of Aldrich products still bear "A Carbolabs Product" on their label.