Appleseed (アップルシード) is a Japanese cyberpunk-style OVA adaptation of the manga of the same name created by Masamune Shirow. The anime takes place in a non-determined future. The anime, produced by Gainax, departs greatly from the manga's storyline, sharing only the characters and setting.
Plot
After World War III, the General Management Control Office constructs an experimental city known as Olympus. It is inhabited by humans, cyborgs, and bioroids. Bioroids are genetically engineered beings created to serve Mankind. They oversee all the administration duties of Olympus. Olympus was meant to be a utopian society, but for some, it feels more like a cage. Charon Mautholos, an Olympus city police officer, is one of the many who feel that way. Charon secretly conspires with a terrorist, A. J. Sebastian, to destroy Gaia, a super computer that runs the various utilities and networks of Olympus. Out to stop them are Olympus City ESWAT (Enhanced SWAT) team members Deunan Knute and Briareos Hecatonchires. Deunan and Briareos are determined to stop the terrorist plot by any means necessary.
A.J. Sebastian and Charon have plotted to disable Gaia, the computer system which controls Olympus' infrastructure, including the override circuits which safeguard Multi-ped Cannon. To do so, they stage a raid on the facility where bioroids are created, creating havoc by killing and by arson. However, it is discovered that the attack is just a cover for stealing information on one particular bioroid, Hitomi, a friend of Deunan and Briareos, whose DNA is the genetic key which will cause Gaia to shut down.